New diagnostic approach to central hypothyroidism after traumatic brain injury in children and adolescents.

Background: Pituitary lesions after traumatic brain injury (TBI) are frequent in children and adolescents, but the rate of post-TBI central hypothyroidism remains uncertain.

Objective: To identify the long-term incidence of post-TBI CH and the clinical and laboratory characteristics of this complication in children and adolescents.

Methods: The analysis included 31 patients with a history of TBI with at least 1 year of follow-up.

Muscle hypertrophy response across four muscles involved in the bench press exercise: Randomized 10 weeks training intervention.

Background And Purpose: Resistance training exercise provides increases in muscle size and is used by coaches and health care professional as a tool to improve functional performance. The aim of the present study was to investigate the effect of 10 weeks of resistance training program performed on the bench press (BP) exercise on the hypertrophic responses of four different muscles (pectoralis major, anterior and medial deltoid, brachii, and pectoralis minor) involved in the task compared to controls.

Methods: Twenty-four healthy males were recruited, and thirteen performed a resistance training intervention while eleven were control.

The bonding situations in ruthenium chalcogenonitrosyl compounds: a physical reasoning.

This research presents, for the first time, a comprehensive and rigorous investigation of ruthenium(II) chalcogenonitrosyl bonding situations in two sets of coordination compounds: [Ru(NE)Cl(L)] (1a-4a) and [Ru(NE)Cl(L)] (1b-4b), where E = O, S, Se, Te. Prior to and following the one-electron reduction, the Ru-NE bonding situations were subjected to analysis. The calculated geometric parameters indicate that both the Ru-NE and N-E bond lengths are susceptible to variation depending on the nature of the chalcogen employed.

E3 Ubiquitin Ligase Smurf1 Regulates the Inflammatory Response in Macrophages and Attenuates Hepatic Damage during Betacoronavirus Infection.

The E3 ubiquitin ligase Smurf1 catalyzes the ubiquitination and proteasomal degradation of several protein substrates related to inflammatory responses and antiviral signaling. This study investigated the role of Smurf1 in modulating inflammation induced by Betacoronavirus infection. Bone marrow-derived macrophages (BMDMs) from C57BL/6 (wild-type) or Smurf1-deficient () mice were infected with MHV-A59 to evaluate the inflammatory response in vitro.

Differential contribution of elbow flexion and knee extension on vascular and hemodynamic parameters and arterial stiffness indices after acute strength exercise in young adults.

Background: Different types of exercise, performed acutely or chronically, have different repercussions on central hemodynamics, arterial stiffness, and cardiac function. In this study, we aim to compare the effects of acute elbow flexion (EFlex) and knee extension (KExt) exercises on vascular and hemodynamic parameters and arterial stiffness indices in healthy young adults.

Methods: Young adults (20 to 39 years) underwent randomized muscle strength tests to obtain 1 repetition maximum (1RM) for elbow flexion (EFlex) and knee extension (KExt).

Structural and Electronic Properties of the Magnetic and Nonmagnetic XMgB (X = Nb, Ni, Fe) Materials: A DFT/HSE06 Approach to Investigate Superconductor Behavior.

MgB material has a simple composition and structure that is well-reported and characterized. This material has been widely studied and applied in the last 20 years as a superconductor in wire devices and storage material for H in the hydride form. MgB doped with transition metals improves the superconductor behavior, such as the critical temperature ( ) or critical current ( ) for the superconducting state.

Pubertal, Auxological, and Adult Height Outcomes in Children Treated for Adrenocortical Tumors: Half a Century Experience.

Introduction: Most children with adrenocortical tumors (ACTs) present with accelerated growth and skeletal maturation at diagnosis, which potentially compromises their adult heights (AHs). Knowledge about growth and pubertal patterns after ACT resection is scarce. This study presents the pubertal and auxological development of patients treated for ACT and followed up at a single pediatric endocrinology service in Brazil.

First record of mercury concentrations and stable isotopes (C & N) in albacore (Thunnus alalunga) from the Western Equatorial Atlantic Ocean.

This paper reports the first record of total mercury (THg) concentrations in albacore (Thunnus alalunga), one of the main tuna species caught from the Western Equatorial Atlantic Ocean and presents a preliminary comparison with other regions and tuna species. Mean, standard deviation and range of concentrations in T. alalunga (515 ± 145 ng g ww; 294-930 ng g ww) with 92 % being of methyl-Hg, are higher than in albacore from other Atlantic Ocean subregions despite their smaller body size.

Mobility, bioavailability and distribution of Fe and Cu in mangroves (Avicennia schaueriana and Rhizophora mangle) from a semiarid coast in NE Brazil.

Mangroves buffer metals transfer to coastal areas though strong accumulation in sediments making necessary to investigate metals' bioavailability to plants at the rhizosphere. This work evaluates the effect of mangrove root activity, through iron plaque formation, on the mobility of iron and copper its influence on metals' uptake, and translocation through simultaneous histochemical analysis. The Fe2+ and Fe3+ contents in porewaters ranged from 0.

Mercury (Hg) concentration in fish commercialized in the São Luís fish market (MA) and potential exposure of consumers.

Fish consumption is the main path of human exposure to Hg and may represent a risk to public health, even with low Hg concentrations in fish, if consumption rates are high. This study quantifies, for the first time, the Hg concentrations in nine most commercialized species in the São Luís (MA) fish market, where fish consumption is high, and estimates human exposure. Average Hg concentrations were highest in carnivorous species, yellow hake (Cynoscion acoupa) (0.

Does rest interval between unilateral exercise protocols influences on contralateral neuromuscular responses in untrained individuals?

Introduction: Effects on strength performance and muscle activation in the contralateral limb have been observed after training with the ipsilateral limb (IL). Cross fatigue effects in the contralateral limb (CL) can occur at intervals of up to 48 h after a training session performed with the ipsilateral limb. The objective of this study was to verify the effect of a training session in the ipsilateral limb, on the strength and activation of the muscles in the contralateral limb also submitted to the training protocol.

Impact of cyclic and continuous dry heat modification on the structural, thermal, technological, and in vitro digestibility properties of potato starch (Solanum tuberosum L.): A comparative study.

Dry heat treatment (DHT) has been demonstrated as a viable method for starch modification, offering benefits due to its environmentally friendly process and low operational costs. This research modified potato starch using different DHT conditions (continuous-CDHT and cyclic-RDHT), with durations ranging from 3 to 15 h and 1 to 5 cycles, at 120 °C. The study investigated and compared the structural, thermal, pasting, and morphological properties of the treated samples to those of untreated potato starch, including in vitro digestibility post-modification.

A 35-Year Record (1987-2022) of Hg Concentrations in Two of the Fish Species Most Consumed by People Living in the Upper Madeira River Basin, Brazilian Amazon Region.

This study presents a 35-year record of total mercury (Hg) concentrations in the detritivore fish (Curimatã) and the carnivore (Tucunaré), two of the most widely distributed, ecologically important and consumed fish species in the upper Madeira River Basin in the Western Brazilian Amazon. Fish samples from the major Madeira River and marginal lakes and tributaries were compared. Irrespective of site, Hg concentrations were higher in the carnivore fish compared to the detritivore.

Trophic ecology of sympatric sea turtles in the tropical Atlantic coast of Brazil.

The Tropical Atlantic coast of Brazil is a hotspot area for multiple sea turtle species at all life stages. The multiple nearshore reefs and beaches, oceanic islands, and the only atoll in the south Atlantic Ocean, are suitable for year-round foraging, migration corridors, and nesting activities of five sea turtle species. Still, relatively few studies have assessed trophic niche among sympatric sea turtles which can provide a better understanding of how closely related species compete/partition the available resources.

Predator-Prey Interaction Between Xylocoris sordidus (Hemiptera: Anthocoridae) and Enneothrips enigmaticus (Thysanoptera: Thripidae).

The peanut thrips, Enneothrips enigmaticus (Thysanoptera: Thrypidae), is an important pest of the peanut (Arachis hypogaea) in South America. Due to concerns about the environment and human health induced by the extensive use of pesticides in the management control of pests, environmentally and friendlier tactics must be targeted. Thus, this study investigates, for the first time, the behavior of Xylocoris sordidus (Hemiptera: Anthocoridae) as a biological control agent for E.

Biological and ecological traits rather than geography control mercury (Hg) in scutes of marine turtles from the Southwest Atlantic.

The use of sentinel species in monitoring programs for toxic metals such as mercury (Hg) is essential to understand these pollutants' impact on the environment. For this purpose, it is essential to use organisms that have a lifespan compatible with the residence time of Hg in the oceans, and preferably with a wide geographical distribution, such as sea turtles. Here, we assess the regional variability of Hg concentrations using carapace scutes of four sea turtle species along the foraging and spawning area in the northeast coastline of Brazil.

Amino Acid Profiles in the Biological Fluids and Tumor Tissue of CRC Patients.

Amino acids are the building blocks of proteins and essential players in pathways such as the citric acid and urea cycle, purine and pyrimidine biosynthesis, and redox cell signaling. Therefore, it is unsurprising that these molecules have a significant role in cancer metabolism and its metabolic plasticity. As one of the most prevalent malign diseases, colorectal cancer needs biomarkers for its early detection, prognostic, and prediction of response to therapy.

Dietary Vitamin D Mitigates Coronavirus-Induced Lung Inflammation and Damage in Mice.

The COVID-19 pandemic caused by the SARS-CoV-2 (β-CoV) betacoronavirus has posed a significant threat to global health. Despite the availability of vaccines, the virus continues to spread, and there is a need for alternative strategies to alleviate its impact. Vitamin D, a secosteroid hormone best known for its role in bone health, exhibits immunomodulatory effects in certain viral infections.

Regional differences in Hg contents in the liver and muscle of the green turtle (Chelonia mydas) from three foraging grounds in Northeast Brazil.

Mercury (Hg) is a highly toxic pollutant that endangers several marine animals, including green sea turtles (Chelonia mydas), particularly in their foraging grounds along Brazilian coastal waters. Environmental Hg levels differ along this extensive littoral, rendering mandatory Hg long-term assessments of the different Hg fate in different sectors of the Brazilian coast. This study quantifies total Hg concentrations in the liver and muscle of green sea turtle populations from three foraging coastal regions in northeastern Brazil and analyzes Hg concentration differences given the locality and size of 61 juvenile individuals sampled.

Corrigendum: Assessment of the accuracy of 11 different diagnostic tests for the detection of in individuals from a Brazilian area of low endemicity using latent class analysis.

[This corrects the article DOI: 10.3389/fmicb.2022.

Effect of Lactate Minimum Speed-Guided Training on the Fluid, Electrolyte and Acid-Base Status of Horses.

The effect of lactate minimum speed (LMS)-guided training on horses' homeostasis is still unknown. Thus, this study aimed to evaluate the effect of an LMS-guided training program on the fluid, electrolyte and acid-base status of horses. Ten untrained Arabian horses were submitted to an LMS test on a treadmill before and after six weeks of training.

Biological basis for adoption of an isoline of Telenomus remus (Hymenoptera: Scelionidae) for an augmentative biological-control program for Spodoptera frugiperda (Lepidoptera: Noctuidae).

The widely distributed, polyphagous fall armyworm, Spodoptera frugiperda (J.E. Smith, 1797), is one of the most important crop pests worldwide.

Impact of Structural GLA Protein Changes on Peripheral GLA Activity and Substrate Accumulation in Fabry Disease Patients.

Introduction: Fabry disease is an X-linked lysosomal storage disorder caused by pathogenic variants in the GLA gene, leading to decreased/absent α-galactosidase activity. In clinical practice, enzyme activity and substrate/byproduct accumulation play a role in diagnosis and disease-monitoring biomarkers. However, interpreting biomarker levels is not straightforward and can change according to the underlying GLA protein abnormality.

Gut microbiota from patients with COVID-19 cause alterations in mice that resemble post-COVID symptoms.

Long-term sequelae of coronavirus disease (COVID)-19 are frequent and of major concern. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection affects the host gut microbiota, which is linked to disease severity in patients with COVID-19. Here, we report that the gut microbiota of post-COVID subjects had a remarkable predominance of strains with an antibiotic-resistant phenotype compared to healthy controls.

Bj-PRO-10c, as an allosteric regulator of argininosuccinate synthase, is a potential therapy for neuroblastoma metastasis.

Cancer is a global public health issue. Neuroblastoma (NB) originates from any tissue of the sympathetic nervous system, and the most affected site is the abdomen. The adrenal gland is the primary site in 38% of cases.