History and development of pediatric otorhinolaryngology in Hungary.

The first pediatric otorhinolaryngological department was set up in Hungary at the Heim Pál Children's Hospital, Budapest in 1948. The first head of the department and the founder of Hungarian pediatric otorhinolaryngology was Ferenc Kallay. He was followed in leadership by Jeno Hirschberg, and at present Gábor Katona.

Synovial sarcoma of the hypopharynx in an 11-year-old boy: treatment by partial supraglottic laryngopharyngectomy.

Synovial sarcoma in an extra-articular location is a very rare tumor, particularly in relation to childhood tumors. We report our experiences with an 11-year-old boy who suffered from swallowing difficulties caused by a polypoid tumor of the hypopharynx. Biopsy demonstrated a fusocellular carcinoma, while the epithelial components showed cytokeratin and neuron-specific enolase positivity.

[Use of the laser in pediatric laryngology].

In several diseases of the upper respiratory tract the use of CO2-laser is effective. Our experience with CO2-laser treatment in 14 children since 1984 is presented. In all cases we could avoid a surgical intervention.

Recombinant interferon-alpha-2C in laryngeal papillomatosis: preliminary results of a prospective multicentre trial.

A preparation of interferon-alpha 2C of high purity formed by recombinant DNA technology was used as adjuvant therapy following removal of laryngeal papillomas by cauterization or laser vaporization. Preliminary data on 20 patients are reported and include 11 complete and 7 partial responses. Side-effects included initial temperature elevation, but this subsided and other side-effects were uncommon.