Publications by authors named "LaQuita N Snow"

Article Synopsis
  • The study aimed to assess the impact of starting antidepressants on viral load suppression in HIV-positive patients with untreated depression.
  • Researchers conducted a retrospective study with 946 patients and found that only 16% started an antidepressant after being diagnosed with depression.
  • The results revealed no significant association between antidepressant use and improved viral load suppression, suggesting that different approaches may be needed for certain patients who do not respond to typical treatments.
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The Johns Hopkins HIV Clinical Cohort, established in 1989, links comprehensive, longitudinal clinical data for adults with HIV receiving care in the Johns Hopkins John G. Bartlett Specialty Practice in Baltimore, Maryland, USA, to aid in understanding HIV care and treatment outcomes. Data include demographics, laboratory results, inpatient and outpatient visit information and clinical diagnoses, and prescribed and dispensed medications abstracted from medical records.

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Objective: It is unclear how often anxiety is diagnosed and treated and whether anxiety treatment is associated with improved viral suppression in persons with HIV. In this study, we characterized the anxiety care continuum and its association with viral suppression in a large urban HIV clinic in the United States.

Design: Observational cohort study.

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Objective: Integrase strand transfer inhibitors (INSTI) are associated with weight gain in people with HIV (PWH), but their impact on diabetes is unclear. We evaluated the association between switching from nonnucleoside reverse-transcriptase inhibitors (NNRTI) or protease inhibitors (PI) to INSTI and incident diabetes.

Design: Longitudinal cohort study.

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Objective: This study sought to characterize changes in depressive symptom severity during the COVID-19 pandemic and the association of these changes with HIV viral nonsuppression among people with HIV (PWH).

Design: A clinical cohort study.

Methods: We included PWH in the Johns Hopkins HIV Clinical Cohort who completed the Patient Health Questionnaire 8 (PHQ-8) prepandemic (1 March 2018 to 28 February 2020) and during the COVID-era (1 September 2020 to 28 February 2022).

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Background: We use a novel, longitudinal approach to describe average time spent in opioid use disorder (OUD) cascade of care stages for people with HIV (PWH) and with OUD, incorporating four definitions of treatment retention. Using this approach, we describe the impact of cocaine or hazardous alcohol use on time spent retained on buprenorphine.

Methods: We followed PWH with OUD enrolled in the Johns Hopkins HIV Clinical Cohort from their first buprenorphine treatment episode between 2013 and 2020.

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Article Synopsis
  • APECED is a genetic disorder linked to autoimmune diseases, with over 40% of affected individuals experiencing pneumonitis, often misdiagnosed despite clear respiratory symptoms.
  • The study highlighted specific autoantibodies and a genetic mutation related to the development of pneumonitis, revealing distinct immune responses in the lungs of these patients.
  • Immunomodulation targeting T and B lymphocytes proved effective in managing symptoms and improving lung function in patients with APECED pneumonitis, demonstrating the significance of understanding lung autoimmunity in this condition.
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