Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi
June 2005
Objective: To study the impact of chronic schistosomiasis on the protective immunity induced by vaccine against hepatitis B virus.
Methods: 24 patients with chronic or advanced schistosomiasis (experimental group) and 26 healthy volunteers (control group) all without hepatitis B virus infection were selected for the study. Sera of the subjects in the two groups were collected before inoculation and on the 35th day after inoculation with yeast-derived recombinant hepatitis B vaccine.