Sustained delivery of growth factors and prostate tissue response - biomed 2010.

Recently, the use of growth factors to repair tissue has shown promising results in areas of musculoskeletal repair. The use of local administration of growth factors has the potential to become systemic and target growth factor sensitive tissue. Prostatic tissue has been shown to be sensitive to insulin like growth hormone-1 (IGF-1) and transforming growth factor beta (TGF-ss).

Sustained delivery of tobramycin via tcpl delivery system to effectively treat osteomyelitis in rats - biomed 2010.

Osteomyelitis is usually treated with systemic antibiotics for prolonged periods of time. These therapies are often unsuccessful with an increase in complication risk to the patient. The development of local antibiotic carriers which are mechanically stable, and can degrade slowly are needed clinically to treat the large number of cases of osteomyelitis seen in a hospital setting.

The role of estrogen, testosterone, and parathyroid hormones in combination with conventional and sustained antioxidant treatment on lncap cells - biomed 2009.

As men age, they will begin to experience numerous changes in their bodies and sometimes these changes are life threatening. Unfortunately, these alteractions can result in protate cancer which tends to be a major public health issue and a leading cause of cancer-related deaths in males (Greenlee et a., 2001).

The evaluation of conventionally delivered tq in csa challenged rmkec - biomed 2009.

At toxic levels, CsA also has the ability to cause renal damage and histological changes that can affect the function of a transplanted kidney. Some of the typical physiological effects of CsA include reduced glomerular filtration and changes in intrarenal hemodynamic function, which can start to occur one week after drug administration. In the early stages of CsA administration kidney damage can occur, which causes alterations in intrarenal hemodynamics related to afferent arteriolar vasoconstriction, causing a decrease in glomerular filtration rate, renal plasma flow, loss of proximal tubular cells brush border, proximal tubule dilatation, swelling, necrosis, and infiltration of white blood cells in the kidney cortex.

A comparison of the morphological changes associated with conventional and sustained treatment with pigallocatechin3gallate, thymoquinone, and tannic acid on lncap cells.

A number of epidemiological studies have suggested that certain antioxidants, such as vitamin E, lycopene, selenium, and their derivatives may be effective in combating prostate cancer and decreasing the risk of prostate cancer in men as well as other cancers in the body. Ongoing research has been targeted towards examining these agents in specific populations and in prostate epithelial cell lines to determine whether risk is reduced and the magnitude of risk reduction (Ni et al., 2007 and Morrissey et al.

The physiological effect of conventional treatment with epigallocatechin-3-gallate, thymoquinone, and tannic acid on the LNCaP cell line.

Antioxidants are substances that function to protect cells from damage caused by unstable free radicals, which are responsible for damage that may lead to cancer. (Blot et al., 1993).

The synergistic effect of conventional and sustained delivery of antioxidants on LNCaP prostate cancer cell line.

Studies have been limited involving antioxidants as a mode of treatment for prostate cancer. The goal of this study was to develop alternative treatment and prevention for the invasive behavior of prostatic mutations by exploring the synergistic effects of several commercially available antioxidants. The specific aims were to examine the viability, proliferation, and morphology of human prostate cells in culture upon treatment of low and high doses of vitamin E, selenium, and lycopene alone or in combination.