Effect of Brewers' Spent Grain Addition to a Fermented Form on Dough Rheological Properties from Different Triticale Flour Cultivars.

Triticale grains and brewers' spent grain (BSG) can be new sources to develop food products. From a socio-economical point of view, this fact is important since triticale is easily adapted to the climatic changes and BSG is a low-cost material which may lead to a "zero-waste" desiderate. In this study, dough rheological properties obtained from different triticale cultivars (Ingen 33, Ingen 35, Ingen 54, and Ingen 93) cultivated in the Republic of Moldova and BSG in a fermented form (BSF) in an addition level of 10% and 17.

Breadmaking Quality Parameters of Different Varieties of Triticale Cultivars.

The aim of this research is to investigate the quality of different triticale cultivars (Ingen 35, Ingen 33, Ingen 93, Ingen 54, Ingen 40, Fanica and Costel) cultivated in the Republic of Moldova from the point of view of the flour, dough, and bread quality characteristics. This research may be of great importance for producers and consumers due to the high production capacity, wide adaptability, economic significance in human foods and nutritional value of triticale cultivars. The triticale flours were analyzed for moisture, ash, protein, wet gluten, fat, carbohydrates, acidity and color parameters (L*, a* and b* values).

Application of molecular framework-based data-mining method in the search for beta-secretase 1 inhibitors through drug repurposing.

Targeting beta-secretase 1, also known as beta-amyloid precursor protein-cleaving enzyme (BACE-1) for the inhibition of amyloid production, has been intensely studied in the last decades in the search for stopping Alzheimer's disease (AD) progression. The chances of finding a druggable BACE-1 inhibitor may be increased by drug repurposing, as this kind of molecules already fulfil certain requirements needed for further advancement. The study describes the development and application of a data-mining method based on molecular frameworks and descriptor values of tested BACE-1 inhibitors, suitable for filtering large compound databases, in order to find molecules with high potency against this protease.

A strain of Plasmodium vivax characterized by prolonged incubation: the effect of numbers of sporozoites on the length of the prepatent period.

The North Korean strain of Plasmodium vivax was characterized by its extraordinarily prolonged incubation period in certain circumstances. It was clearly demonstrated by quantitative observations that the phenomenon may be elicited by the inoculation of small numbers of sporozoites. After the intradermal inoculation of 10 or 100 sporozoites, the incubation period was delayed for periods varying between 262 and 628 days; after u,000 sporozoites, with one exception, the same delay occurred; after 100,000 sporozoites, the incubation period was always of normal duration (13--16 days).

Sources of hepatitis B virus infection in hospital environment.

Investigations on the incidence of hepatitis B antigen (HB Ag)-carriers among 1466 patients of 11 various hospitals and departments showed that sources of hepatitis infection were more numerous in hospitals for children than in those for adults. The high-risk departments were those of dialysis (5 out of 12 patients), clinical medicine (6.6%), and obstetrics and gynecology, for adults, and those of neuropsychiatry (17.