Biliary anionic peptide fraction and apoA-I regulate intestinal cholesterol uptake.

Evidence is now in favor of protein-facilitated mechanisms for the intestinal cholesterol absorption. Here we report that the unesterified cholesterol uptake by rat jejunal brush border membrane vesicles (BBMVs) is efficient, saturable, and protein-mediated. The human apolipoproteins biliary anionic peptide factor (APF) and A-I (apoA-I) up-regulate micellar cholesterol uptake in a dose-dependent manner, but for all tested concentrations (0.

[Serum lipids and proteins in newborn infants in Ivory Coast].

This study has permitted, from samples of the cord of 521 newborns in the Ivory Coast, to determine the average values of the following blood parameters: total proteins, total cholesterol, triglycerides, uric-acid, natrium, high density lipoproteins (HDL), very low density lipoproteins (VLDL), low density lipoproteins (LDL), HDL cholesterol (HDLC), VLDL cholesterol (VLDL-C), LDL cholesterol (LDLC), albumin, alpha 1, alpha 2, beta and gammaglobulins. Variations of the biochemical parameters in function of sex, social standard and races, as well as the correlations between the lipidic and protidic parameters were set forth.

[1-year monitoring of the course of chronic renal insufficiency induced by subtotal nephrectomy in rats. Pharmacokinetic value].

A subtotal nephrectomy is realized on 200 rats Wistar IOPS, producing a chronical renal failure (CRF). Evolution is studied during 12 months and compared to 100 normal rats of the same age. Biochemical criteria show an increased blood urea and creatinemia with a diminution of creatinin clearance and an appearance of important proteinuria.