Visual and Anatomical Outcomes of a Single Intravitreal Dexamethasone in Diabetic Macular Edema: An 8 Year Real-World Study.

Importance: Diabetic macular edema (DME) is a major cause of vision loss in patients with diabetes mellitus. Intravitreal dexamethasone is a treatment option for patients unsuitable for or non-responsive to anti-angiogenic agents.

Objective: To quantify visual and anatomical outcomes from an initial intravitreal dexamethasone injection over the expected 6-month period of dexamethasone release by the implant.

Deep-learning automated quantification of longitudinal OCT scans demonstrates reduced RPE loss rate, preservation of intact macular area and predictive value of isolated photoreceptor degeneration in geographic atrophy patients receiving C3 inhibition treatment.

Objective: To evaluate the role of automated optical coherence tomography (OCT) segmentation, using a validated deep-learning model, for assessing the effect of C3 inhibition on the area of geographic atrophy (GA); the constituent features of GA on OCT (photoreceptor degeneration (PRD), retinal pigment epithelium (RPE) loss and hypertransmission); and the area of unaffected healthy macula.To identify OCT predictive biomarkers for GA growth.

Methods: Post hoc analysis of the FILLY trial using a deep-learning model for spectral domain OCT (SD-OCT) autosegmentation.

Marriage contributes to higher obesity risk in China: findings from the China Health and Nutrition Survey.

Background: To investigate the association between marriage and the prevalence of overweight and obesity in China.

Methods: We conducted cross-sectional and retrospective cohort analyses using a nationwide sample of 36,310 individuals from the China Health and Nutrition Survey [2004-2015].

Results: The prevalence of overweight and obesity increased from 28.

Evaluation of work resumption strategies after COVID-19 reopening in the Chinese city of Shenzhen: a mathematical modeling study.

Objectives: As China is facing a potential second wave of the epidemic, we reviewed and evaluated the intervention measures implemented in a major metropolitan city, Shenzhen, during the early phase of Wuhan lockdown.

Study Design: Based on the classic SEITR model and combined with population mobility, a compartmental model was constructed to simulate the transmission of COVID-19 and disease progression in the Shenzhen population.

Methods: Based on published epidemiological data on COVID-19 and population mobility data from Baidu Qianxi, we constructed a compartmental model to evaluate the impact of work and traffic resumption on the epidemic in Shenzhen in various scenarios.

A systematic review, and meta-analysis, examining the prevalence of price promotions on foods and whether they are more likely to be found on less-healthy foods.

Objective: There are concerns that price promotions encourage unhealthy dietary choices. This review aims to answer the following research questions (RQ1) what is the prevalence of price promotions on foods in high-income settings, and (RQ2) are price promotions more likely to be found on unhealthy foods?

Design: Systematic review of articles published in English, in peer-review journals, after 1 January 2000.

Setting: Included studies measured the prevalence of price promotions (i.

[Comparison of basic physical measurements in Czech and Slovak children and adolescents].

The authors compared the Slovak and Czech part of the IVth nation-wide anthropological survey of children and youth from birth to the age of 18 years and evaluated the revealed differences in height, body weight, head and chest circumferences. The results confirm the assumed further approximation of growth values of the two child populations and the gradual equalization recorded in particular in the youngest age groups.

[The effect of air pollution on the occurrence of respiratory tract diseases in children in Slovakia].

In 1986 and 1987 the authors investigated the incidence of diseases of the respiratory system in children in 13 areas with a contaminated atmosphere. The morbidity was compared with the incidence of diseases in children living in an area with a relatively clean living environment. In 1986 the group comprised 8,973 children, in 1987 9,409 children aged 7-14 years.

On the mechanism of acute toxicity of phosmet.

Rats were given single oral doses of phosmet (LD50 or 3/4 LD50). Changes of hematological parameters were studied in several time intervals; the main interest was paid to disturbances in blood clotting. Both light and electron microscopy were used to evaluate histopathological changes in selected organs (liver, lungs, spleen, stomach).