Comparison of two sucralfate dosages presented in tablet form in duodenal ulcer healing.

Two hundred twenty-two patients with endoscopically proven duodenal ulcers participated in a controlled trial to assess and compare the effects of two dosage regimens of sucralfate tablets on ulcer healing, i.e., 1 g four times daily (group A, n = 131) and 2 g twice daily (group B, n = 128).

[Non-surgical treatment of hemorrhoids].

The treatment of hemorrhoids includes a vast array of medical and instrumental means. If there is no true medical treatment, there are numerous products in order to act on the symptoms or one of the factors of the hemorrhoidal complex. Thus, phlebotonics, local topical agents, anti-infectious and anti-inflammatory agents, myorelaxants, transit regulators.

[Maintenance therapy of ulcer disease. Comparative multicenter study of sucralfate, cimetidine and a placebo].

Relapse rates were studied in one hundred patients in a multicentric, randomized trial during and after maintenance therapy comparing sucralfate, cimetidine and placebo. These patients were previously treated by cimetidine for peptic ulcer and were considered cured after endoscopic examination. Outpatients were randomly assigned to a 6 month maintenance treatment with either cimetidine (600 mg daily), sucralfate (300 mg daily) or a placebo.

[Anorectal manifestations of sexually transmissible diseases. Kaposi's sarcoma].

The proctologist is above all concerned with the known recrudescence of venereal diseases. Examples reviewed are diseases of bacterial origin (syphilis, gonorrhea, soft chancre, donovanosis and chlamydiosis), appropriate antibiotic therapy and diseases of viral origin (herpes, condyloma acuminatum). Also noted are other bacterial, viral and parasitic diseases and, indeed, cancers of which Kaposi's sarcoma is the example, even though these are not manifested anorectally.

[Apparently primary malignant lymphoma of the rectum. Presentation of a case].

With reference to a case of apparently primary lymphoma of the rectum, the authors emphasize the difficulty of diagnosis, which requires deep biopsies, and of categorizing clinical cases in view of the constantly modified classifications. Treatment modalities, whose choice is dependent upon the disease itself and the general state of health of the individual patient, are summarized.

Maintenance treatment of patients with healed peptic ulcer with sucralfate, placebo and cimetidine.

Preliminary data from a randomised, placebo-controlled, multicenter study suggest that maintenance therapy with sucralfate reduces the rate of the recurrent ulceration in patients with recently healed ulcers.

[Syndrome of inappropriate antidiuretic hormone secretion. A report of two cases with hyponatremia and hypouricemia].

Two cases of Schwartz-Bartter syndrome are reported. Both were due to malignant anaplasic tumours of the APUD type with multiple abnormal endocrine secretion, and both were accompanied with hypouricaemia of uncertain significance. The authors believe that the association of hypernatraemia with hypouricaemia should alert clinicians to the possibility of a syndrome of inappropriate antidiuretic hormone secretion (SIADH) of malignant origin.

Chronic non-specific ulcerative duodenojejunoileitis: report of four cases.

Four patients with chronic non-specific ulcerative duodenojejunoileitis (CNSUDJI) are reported. The clinical picture included abdominal pain, fever, and a malabsorption syndrome. Main rediological findings were diffuse narrowing of the jejunal loops with total effacement of the mucosal folds.

[Gastrointestinal haemorrhage in the cirrhotic. The value of injectable posterior pituitary extract (author's transl)].

The authors report the experience which the have acquired since 1970 in the use of posterior pituitary extract as part of the treatment of gastrointestinal bleeding in cirrhotics. 100 cases have been collected, in 73 patients. These may be divided into two groups: one of 32 patients, who did not receive posterior pituitary extract, with 31 deaths, and one of 41 patients who did receive the extract, with 6 deaths.

[The excision of villous tumours of the rectum via a trans-sphincterian anal approach (author's transl)].

Cleavage in the thickness of the internal sphincter and of the circular layer of the rectum is performed. By progressive drawing down, this method makes it possible to obtain complete excision, passing at a distance from the tumour in its different planes.