Experience with Norcuron, a muscle relaxant of average duration of neuro-muscular effect.

In course of the anaesthesia of orthopaedic and general surgery operations, the author administered Norcuron injection in 80 cases for the purpose of intubation and/or surgical myorelaxation. On account of the observation of the usual parameters, he found Norcuron to be a product meeting the expectations, furnishing myorelaxation of medium length that did not cause adverse alterations, in circulation neither did it have other unpleasant side- or after-effect. The author applied a so-called priming dose system by which the time required for intubation could be appreciably shortened.

Role of domperidone in improving intestinal activity in acute myocardial infarction patients.

Domperidone has been used as a gastrokinetic and anti-emetic drug within the frames of an intensive care programme in 57 patients with a history of 3-4 days of acute myocardial infarction. According to the observations, Motilium prevents the development of gastroduodenal complaints and nausea, vomiting in a period following the first days of acute therapy and promotes the start of bowel movement and defecation. It has no cardiac or other toxic effects and does not influence the action of other drugs.

[Clinical importance of cardiac output dissociation between the right and left ventricle without evidence of an anatomical shunt].

Authors took note of transitoric cardiac output dissociation between the right and left ventricle during the treatment of the acute myocardial infarction controlled hemodynamically, without the presence of a provable anatomical shunt. They demonstrate some kinds of clinical appearances and call the attention to the clinical importance of the progressive cardiac output dissociation. The re-establishment of balance of the right and left cardiac output in resting position at the most optimal level of the oxygen demand, simultaneously the correction of the blood pressure and blood volume correlation can help the treatment of such acute cardiovascular cases which are complicated hemodynamic disturbances.

The importance of domperidone (Motilium) in controlling postoperative nausea and vomiting.

Comparative study was performed for assessing the postoperative anti-emetic and emesis preventive effect of domperidone. It has been found that the emesis preventive effect of Motilium tablet is identical with the effect of the well known Daedalon (Dramamin) and Torecan. From the therapeutic aspect it is of value especially in controlling nausea and in the prevention of subsequent vomiting following the use of rectal anti-emetics.