Publications by authors named "L van Rossem"
Article Synopsis
- The study focuses on how the intake of polyunsaturated fatty acids (PUFAs) during the periconceptional period affects embryonic development, particularly embryonic volume (EV) and head volume (HV) in pregnant women.* -
- Findings reveal that many women have low omega-3 intake, and while higher PUFA intake is linked to a smaller HV/EV ratio, it does not correlate with individual EV or HV growth measures.* -
- The research highlights a significant omega-3 deficiency in pregnant women and emphasizes the need for better awareness of PUFA intake to mitigate risks of negative pregnancy outcomes.*
Developing an effective and simple digital screening tool to identify inadequate calcium intake in pregnant women: A prediction model in the Rotterdam periconception cohort.
Eur J Obstet Gynecol Reprod Biol
November 2024
Objectives: An inadequate intake of calcium in pregnancy is associated with higher risks of maternal hypertensive pregnancy disorders, premature birth and intrauterine growth restriction. An evidence based and clinically applicable tool to efficiently estimate the adequacy of calcium intake in pregnant women currently does not exist. The aim of this study is to develop an effective and simple digital screening tool for calcium intake in pregnancy.
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- Hypertensive disorders of pregnancy (HDP) are major contributors to complications in pregnancy, prompting research into the role of maternal tryptophan metabolites in placental health and development.
- The study involved 911 women and assessed serum tryptophan metabolites early in pregnancy, analyzing their relationships with placental volume and vascular development, as well as odds of developing HDP.
- Findings showed that higher kynurenine levels negatively impacted placental development, while increased levels of 5-hydroxytryptophan were linked to higher risks of early pregnancy hypertension and preeclampsia.
Background & Aims: The quantity and quality of maternal nutrition in the periconception period is an important determinant for embryonic and foetal development and subsequent pregnancy course and outcome. The intake of ultra-processed foods (UPF) has increased worldwide and adverse health outcomes have been reported. However, the impact of UPF intake on the placenta, essential for prenatal nourishment, is unknown.
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- - The study looks at whether stress hormones in pregnant women, called maternal vulnerability, can affect their baby's growth in the first trimester.
- - Researchers found that higher levels of certain stress hormones in hair were linked to slower growth of the baby, while another substance called tryptophan was lower when stress was higher.
- - The study used data from 132 pregnant women over a year to create a risk score for how vulnerable they are to stress and how it impacts their pregnancies.