Publications by authors named "L van Niftrik"
Article Synopsis
- Capsids of the cowpea chlorotic mottle virus (CCMV) show potential as therapeutic nanocarriers, but their instability at physiological pH has limited cargo incorporation methods.
- Researchers developed a method using a stabilized variant of the CCMV coat protein, co-expressing it with proteins like mEGFP in E. coli for effective cargo loading.
- The results demonstrated that the co-expression process does not harm E. coli cells and ensures proper folding of the mEGFP, making this strategy viable for producing cargo-loaded CCMV nanoparticles.
The application of partial nitritation-anammox (PN/A) under mainstream conditions can enable substantial cost savings at wastewater treatment plants (WWTPs), but how process conditions and cell physiology affect anammox performance at psychrophilic temperatures below 15 °C remains poorly understood. We tested 14 anammox communities, including 8 from globally-installed PN/A processes, for (i) specific activity at 10-30 °C, (ii) composition of membrane lipids, and (iii) microbial community structure. We observed that membrane composition and cultivation temperature were closely related to the activity of anammox biomasses.
View Article and Find Full Text PDFThe adaptation of bacteria involved in anaerobic ammonium oxidation (anammox) to low temperatures will enable more efficient removal of nitrogen from sewage across seasons. At lower temperatures, bacteria typically tune the synthesis of their membrane lipids to promote membrane fluidity. However, such adaptation of anammox bacteria lipids, including unique ladderane phospholipids and especially shorter ladderanes with absent phosphatidyl headgroup, is yet to be described in detail.
View Article and Find Full Text PDFThe Streptococcus pneumoniae capsule is regarded as indispensable in bacteremia. We report an infant with a ventricular septal defect and infective endocarditis caused by nontypeable S. pneumoniae.
View Article and Find Full Text PDFLate cornified envelope proteins are predominantly expressed in the skin and other cornified epithelia. On the basis of sequence similarity, this 18-member homologous gene family has been subdivided into six groups. The LCE3 proteins have been the focus of dermatological research because the combined deletion of LCE3B and LCE3C genes (LCE3B/C-del) is a risk factor for psoriasis.
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