Publications by authors named "L van Hulsteijn"
Article Synopsis
- - Glucocorticoids are commonly used medications for inflammation and immune suppression, but over 1% of users may face a risk of adrenal insufficiency based on dosage, duration, and individual factors.
- - Managing adrenal insufficiency can be complex, especially when trying to taper off glucocorticoids, as withdrawal symptoms can mimic those of adrenal insufficiency.
- - A new joint guideline from the European Society of Endocrinology and Endocrine Society offers important recommendations for healthcare providers to effectively care for patients undergoing long-term glucocorticoid therapy.
Article Synopsis
- * The risk of developing this condition varies based on factors like dosage, duration, and individual responses, making patient education and management essential once adrenal insufficiency is suspected.
- * Tapering glucocorticoids can be complicated by overlapping withdrawal symptoms; hence, guidelines suggest a faster taper from high doses followed by a slower reduction at lower, physiological levels.
Introduction: Women with a current diagnosis or past history of Graves' disease (GD) are at risk of developing fetal thyrotoxicosis (FT) during pregnancy when they are inadequately treated, or because of placental passage of TSH receptor antibodies (TRAb). It is known that FT induced by high maternal thyroid hormone concentrations may result in infant (central) hypothyroidism.
Case Presentation: In a euthyroid woman with a history of GD treated with radioactive iodide (I131), persistently high levels of maternal TRAb resulted in recurrent FT during two separate pregnancies, followed by neonatal hyperthyroidism and infant central hypothyroidism.
Obesity is an emerging condition, with a prevalence of ~20%. Although the simple measurement of BMI is likely a simplistic approach to obesity, BMI is easily calculated, and there are currently no data showing that more sophisticated methods are more useful to guide the endocrine work-up in obesity. An increased BMI leads to a number of hormonal changes.
View Article and Find Full Text PDFObjective: The increasing prevalence of obesity is expected to promote the demand for endocrine testing. To facilitate evidence guided testing, we aimed to assess the prevalence of endocrine disorders in patients with obesity. The review was carried out as part of the Endocrine Work-up for the Obesity Guideline of the European Society of Endocrinology.
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