Endocrinologic Dysfunctions and Neuropsychiatric Sequelae in Pediatric Patients With a History of Central Nervous System Infection (ENDLESS): A Prospective Monocentric Study.

Introduction: Central nervous system (CNS) infections represent some of the most critical pediatric health challenges, characterized by high mortality rates and a notable risk of long-term complications. Despite their significance, standardized guidelines for endocrinological follow-up of CNS infection survivors are lacking, leading to reliance on the expertise of individual centers and clinicians.

Materials And Methods: Prospective monocentric observational study conducted at the Fondazione Policlinico Universitario Agostino Gemelli in Rome, Italy.

Immunomodulatory Properties of Multi-Strain Postbiotics on Human CD14 Monocytes.

The ability of probiotics, comprising live microbiota, to modulate the composition of intestinal microbiomes has been connected to modulation of the central nervous system (Gut-Brain axis), neuroendocrine system (Gut-Skin axis), and immune response (Gut-Immune axis). Less information is known regarding the ability of postbiotics (cell wall components and secreted metabolites derived from live organisms) to regulate host immunity. In the present study, we tested postbiotics comprising single strains of bacteria and yeast ( 16axg, 18fx, 16mxg) as well as combinations of multiple strains for their ability to stimulate cytokine production by human CD14 monocytes.

Salvia pratensis L. extracts as potential eco-friendly herbicides for sustainable agricultural applications.

The aim of this study is based on the searching of "new" potential environmentally friendly plant based products with herbicidal activity. The purpose of the study is also to find the source which is easy to harvest in high amount within the local environment. Salvia pratensis L.

Composition and antimicrobial activity of hydroalcoholic extracts of var. and var. .

Background: The basidiomycetes var. Lanzi and var. Venturella et al.

Does EFSA statement on Monacolin content of nutraceutical combinations impair their lipid lowering effect? The LopiGLIK experience.

Background: Monacolin-K, the active component of red yeast rice (RYR), reduces cholesterol by inhibiting HMG-CoA reductase. Following safety concerns, the European Food Safety Authority (EFSA) recommended limiting Monacolin-K intake to less than 3 mg/day due to adverse effects at higher doses.

Case Presentation: A study comparing Armolipid Plus and LopiGLIK found LopiGLIK more effective in lowering LDL cholesterol, possibly due to slightly higher dosages of Berberine and Monacolin-K.