Publications by authors named "L Zurba"
Article Synopsis
- Rapid urbanization in sub-Saharan Africa is linked to a rise in asthma cases among children and teens, particularly due to challenges in obtaining clinical diagnoses for those exhibiting symptoms.* -
- A two-phase study was conducted across multiple countries involving adolescents aged 12-14, where asthma symptoms were assessed through a questionnaire, and further evaluations were carried out on those with symptoms, including tests for lung function and environmental risk factors.* -
- The study aimed to gather data on the prevalence and severity of asthma in symptomatic adolescents, alongside objective testing methods like spirometry and fractional exhaled nitric oxide (FeNO) to better understand asthma's impact on daily life.*
Background: Tuberculosis remains a global health concern, and half of cured patients have permanent lung injury. N-acetylcysteine (NAC) has shown beneficial antimicrobial, antioxidant, and immunomodulatory effects in preclinical tuberculosis models. We examined its effects on tuberculosis treatment outcomes.
View Article and Find Full Text PDFIntroduction: Contemporary data on the burden of chronic respiratory diseases in sub-Saharan Africa is limited. More so, their economic burden is not well described. This study aims to establish a chronic respiratory disease observatory for Africa.
View Article and Find Full Text PDFBackground: Sequelae post-SARS-CoV-2 infection, including lung and functional impairment, pose a significant challenge post-recovery. We explored the burden and risk factors for post-COVID-19 sequelae in an African population with prevalent comorbidities including tuberculosis (TB) and HIV.
Methods: We conducted an observational cohort study on hospitalised adults with confirmed SARS-CoV-2 infection from 20 March to 06 October 2021 at Chris Hani Baragwanath Academic Hospital, South Africa.
Decreased prevalence and severity of asthma symptoms among adolescents in Ibadan, Nigeria, 1995-2018.
Int J Tuberc Lung Dis
December 2023
Phases I and III of the International Study of Asthma and Allergies in Childhood (ISAAC) documented increased asthma symptoms among Nigerian 13-14-year old adolescents. We investigated the trend further using the Global Asthma Network (GAN) surveillance. Using ISAAC methodology, GAN Phase I data on symptoms and risk factors for asthma and asthma management were obtained from February to July 2018.
View Article and Find Full Text PDF