Modeling Lanthanide Ions in Solution: A Versatile Force Field in Aqueous and Organic Solvents.

In this paper, we propose a new nonpolarizable force field for describing the Ln (Ln = lanthanide) series based on a 12-6-4 Lennard-Jones potential. The development of the force field was performed in pure water by adjusting both the ion-oxygen distance and the hydration free energy. This force field accurately reproduces the Ln hydration properties through the series, especially the coordination number that is hardly accessible using a nonpolarizable force field.

Simultaneous determination of free biliverdin and free bilirubin in serum: A comprehensive LC-MS approach.

Background: Prognosis, diagnosis, and treatment of several diseases strongly rely on the sensitive, selective, and accurate determination of specific biomarkers in relevant biological samples. Free biliverdin and free bilirubin represent important new biomarkers of oxidative stress, however, the lack of suitable analytical methods for their determination has hindered progress in biomedical and clinical research.

Results: Here, we introduce a first comprehensive approach for robust and simultaneous determination of these bilins in serum using liquid chromatography - mass spectrometry (LC-MS).

Sarcopenic obesity and hypertension in elderly patients: a narrative review of pathophysiology and management strategies.

Introduction: Sarcopenic obesity and hypertension are a public health problem that is increasing worldwide due to the progressive aging of the population and the increasing prevalence of obesity and physical inactivity. Sarcopenic obesity is characterized by the simultaneous presence of sarcopenia (loss of muscle mass) and adiposity (increase in fat mass). Because symptoms are not specific, sarcopenic obesity remains largely undiagnosed.

Experimental measurements of the viscosity and melt structure of alkali basalts at high pressure and temperature.

Volcanic eruptions are shallow phenomena that represent the final stage of density- and viscosity- driven processes of melt migration from source rocks at upper mantle depths. In this experimental study, we investigated the effect of pressure (0.7-7.

NaYF-based upconverting nanoparticles with optimized phosphonate coatings for chemical stability and viability of human endothelial cells.

The increasing interest in upconverting nanoparticles (UCNPs) in biodiagnostics and therapy fuels the development of biocompatible UCNPs platforms. UCNPs are typically nanocrystallites of rare-earth fluorides codoped with Yband Eror Tm. The most studied UCNPs are based on NaYFbut are not chemically stable in water.