Publications by authors named "L Zajdenverg"
Objective: To assess the frequency and potential influencing factors of the remission phase (RP) in Type 1 Diabetes (T1D) as well as the associations between various criteria used for its definition.
Methods: This was a retrospective cohort study based on data collected from medical records. Three criteria were used to evaluate RP: (1) Glycated hemoglobin (HbA1c) < 7.
Telephone lifestyle intervention to prevent diabetes in women with recent gestational diabetes mellitus attending the national health system: the LINDA-Brasil clinical trial.
BMJ Open
October 2024
Objectives: To evaluate a postpartum telephone-based lifestyle intervention to prevent diabetes in high-risk women with recent gestational diabetes mellitus (GDM).
Design: Multicentre parallel randomised clinical trial.
Setting: Specialised antenatal clinics in the Brazilian National System.
Article Synopsis
- The systematic review evaluated how periodontal therapy affects inflammation and oxidative stress markers in type 2 diabetes patients with periodontitis.
- Reviews of 1,062 studies identified 14 eligible trials with 1,223 participants, showing moderate-quality evidence that periodontal treatment lowers c-reactive protein levels, a marker of inflammation, particularly notable in smokers.
- The findings suggest that non-surgical periodontal therapy can reduce systemic inflammation in T2DM patients, potentially lowering risks for other serious conditions like cardiovascular disease.
Objectives: To evaluate the association between perinatal and obstetric factors as potential triggers for the early onset of T1DM.
Methods: This was a retrospective cohort study enrolling 409 patients diagnosed with T1DM, in Bauru, São Paulo, Brazil, from 1981 to 2023. Data were retrieved from medical records, regarding sociodemographic parameters as age, sex, ethnicity, and socioeconomic status.
Article Synopsis
- - The study investigates familial partial lipodystrophy (FPLD) in Brazil, focusing on its clinical, metabolic, and genetic characteristics through a multicenter analysis involving 106 patients.
- - Results show a high prevalence of diabetes (57.5%), severe hypertriglyceridemia (34.9%), metabolic-associated fatty liver disease (56.6%), and a notable mortality rate linked to cardiovascular issues (3.8%).
- - The findings highlight the need for better understanding and management of FPLD, particularly due to the serious health complications associated with the disorder in this population.