Motivational drivers and emotions that students experience play an important role in the process of learning a new language (L2). This has been recognised by researchers and educators, and extensive research has been conducted in recent decades to examine the psychological and emotional factors involved in L2 learning. However, two ubiquitous epistemic emotions, namely, boredom and curiosity, remain underexplored in the L2 research literature.
View Article and Find Full Text PDFSpectrochim Acta A Mol Biomol Spectrosc
February 2025
The design of fluorescent probes based on biocompatible luminophores for medical diagnostics is one of the rapidly developing areas worldwide. Here, we report the synthesis of a novel BODIPYs containing a propanoic acid residue at the α-position of one of the pyrrole rings conjugated to (+)-myrtenol or thiotherpenoid. Both conjugates are quite photostable (t ∼ 40 h) and exhibit high fluorescence efficiency (φ ∼ 77-90 %).
View Article and Find Full Text PDFVestn Oftalmol
September 2024
Lead and cadmium are heavy metals widely distributed in the environment and contribute significantly to cardiovascular morbidity and mortality. Using Leadmium Green dye, we have shown that lead and cadmium enter cardiomyocytes, distributing throughout the cell. Using an motility assay, we have shown that sliding velocity of actin and native thin filaments over myosin decreases with increasing concentrations of Pb and Cd.
View Article and Find Full Text PDFThe disuse of skeletal limb muscles occurs in a variety of conditions, yet our comprehension of the molecular mechanisms involved in adaptation to disuse remains incomplete. We studied the mechanical characteristics of actin-myosin interaction using an in vitro motility assay and isoform composition of myosin heavy and light chains by dint of SDS-PAGE in soleus muscle of both control and hindlimb-unloaded rats. 14 days of hindlimb unloading led to the increased maximum sliding velocity of actin, reconstituted, and native thin filaments over rat soleus muscle myosin by 24 %, 19 %, and 20 %, respectively.
View Article and Find Full Text PDF