Publications by authors named "L Y He"

Importance: Lupus nephritis is typically treated with intravenous cyclophosphamide, which is associated with serious adverse effects. Oral mizoribine may be an alternative for induction therapy of lupus nephritis. However, large-scale, long-term, randomized clinical studies of mizoribine are lacking.

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Purpose: The management of chronic lymphocytic leukemia (CLL) has significantly improved with targeted therapies. However, many patients experience a suboptimal response. To optimally select the best therapy, predictive biomarkers are necessary.

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Objectives: The genetic variant rs13137 of miR-21 is associated with susceptibility in many diseases. However, the association with cognitive dysfunction (CD) in Chinese patients with systemic lupus erythematosus (SLE) remains unclear.

Materials And Methods: Two hundred and thirty SLE patients (Non-CD) and 230 SLE-related CD patients (CD) were recruited.

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Background: Aortic coarctation (CoA) is a congenital heart disease that usually combines various cardiovascular malformations, including hypoplastic aortic arch (HAA). We explore end-to-side anastomosis (ESA) and autologous pulmonary artery patch (APAP) in CoA with HAA, to provide more clinical experience.

Methods: This is a single-center retrospective study.

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Background: Patients with chronic kidney disease (CKD) are considered the primary population at risk for post-contrast acute kidney injury (PC-AKI), yet there are few predictive tools specifically designed for this vulnerable population.

Methods: Adult CKD patients undergoing coronary angiography or percutaneous coronary intervention at the Second Xiangya Hospital (2015-2021) were enrolled. The patients were divided into a derivation cohort and a validation cohort based on their admission dates.

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