Importance: Lupus nephritis is typically treated with intravenous cyclophosphamide, which is associated with serious adverse effects. Oral mizoribine may be an alternative for induction therapy of lupus nephritis. However, large-scale, long-term, randomized clinical studies of mizoribine are lacking.
View Article and Find Full Text PDFPurpose: The management of chronic lymphocytic leukemia (CLL) has significantly improved with targeted therapies. However, many patients experience a suboptimal response. To optimally select the best therapy, predictive biomarkers are necessary.
View Article and Find Full Text PDFObjectives: The genetic variant rs13137 of miR-21 is associated with susceptibility in many diseases. However, the association with cognitive dysfunction (CD) in Chinese patients with systemic lupus erythematosus (SLE) remains unclear.
Materials And Methods: Two hundred and thirty SLE patients (Non-CD) and 230 SLE-related CD patients (CD) were recruited.
Background: Aortic coarctation (CoA) is a congenital heart disease that usually combines various cardiovascular malformations, including hypoplastic aortic arch (HAA). We explore end-to-side anastomosis (ESA) and autologous pulmonary artery patch (APAP) in CoA with HAA, to provide more clinical experience.
Methods: This is a single-center retrospective study.
Background: Patients with chronic kidney disease (CKD) are considered the primary population at risk for post-contrast acute kidney injury (PC-AKI), yet there are few predictive tools specifically designed for this vulnerable population.
Methods: Adult CKD patients undergoing coronary angiography or percutaneous coronary intervention at the Second Xiangya Hospital (2015-2021) were enrolled. The patients were divided into a derivation cohort and a validation cohort based on their admission dates.