Size effect-based improved antioxidant activity of selenium nanoparticles regulating Anti-PI3K-mTOR and Ras-MEK pathways for treating spinal cord injury to avoid hormone shock-induced immunosuppression.

Spinal cord injury (SCI) is a critical condition affecting the central nervous system that often has permanent and debilitating consequences, including secondary injuries. Oxidative damage and inflammation are critical factors in secondary pathological processes. Selenium nanoparticles have demonstrated significant antioxidative and anti-inflammatory properties via a non-immunosuppressive pathway; however, their clinical application has been limited by their inadequate stability and functionality to cross the blood-spinal cord barrier (BSCB).

Effectiveness and user experience of nose and throat swabbing techniques for SARS-CoV-2 detection: results from the UK COVID-19 National Testing Programme.

Background: The UK's National Health Service Test and Trace (NHSTT) program aimed to provide the most effective and accessible SARS-CoV-2 testing approach possible. Early user feedback indicated that there were accessibility issues associated with throat swabbing. We report the results of service evaluations performed by NHSTT to assess the effectiveness and user acceptance of swabbing approaches, as well as qualitative findings of user experiences from research reports, surveys, and incident reports.

Triboelectric Bending Sensors for AI-Enabled Sign Language Recognition.

Human-machine interfaces and wearable electronics, as fundamentals to achieve human-machine interactions, are becoming increasingly essential in the era of the Internet of Things. However, contemporary wearable sensors based on resistive and capacitive mechanisms demand an external power, impeding them from extensive and diverse deployment. Herein, a smart wearable system is developed encompassing five arch-structured self-powered triboelectric sensors, a five-channel data acquisition unit to collect finger bending signals, and an artificial intelligence (AI) methodology, specifically a long short-term memory (LSTM) network, to recognize signal patterns.

Molecular Identification of Infection Using Nanopore Sequencing: A Case Report and Literature Review.

(previously known as ) infection is not common in Hong Kong. is a fish-borne cestode parasite that infects humans after consuming raw or insufficiently cooked fish containing plerocercoids. We reported a case of infection in a 40-year-old woman who presented with a complaint of epigastric pain and diarrhea.