Publications by authors named "L Wyllie"

Article Synopsis
  • This study investigates the real-world application of treatment intensification beyond androgen-deprivation therapy (ADT) in older men with metastatic castration-sensitive prostate cancer (mCSPC) in Ontario, Canada.
  • A cohort of 3556 patients from 2014 to 2019 showed that 78.6% were treated with standard ADT, while only 11.2% received ADT plus docetaxel and 1.5% received ADT with abiraterone acetate, indicating low uptake of intensified treatment.
  • Despite evidence suggesting better outcomes with intensified therapy, most patients in the study still received only ADT, highlighting the need for improved understanding of barriers to treatment
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Embryonic liver cells of chicken have been cultivated in medium more or less supplemented with serum. With a rich medium mitochondria become larger and often ramify. Their fundamental structure remains normal.

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Human fetal lung obtained from 9-26 = weeks = old embryos were maintained in organ culture for 2-5 weeks. The in vitro survival and changes are clearly age dependent. The best survival was obtained with lung tissue from the early glandular period.

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