Publications by authors named "L Worthington"
Article Synopsis
- * Researchers analyzed fecal samples from 18 anemic and 20 control infants at various postnatal ages, revealing that severe anemia correlates with increased virulence factors and significant alterations in gut metabolites.
- * Findings suggest that severe anemia leads to a pro-inflammatory gut microbiome with more harmful bacterial activities, highlighting the need for further research on how these gut changes affect the health outcomes of preterm infants.
Article Synopsis
- Group B Streptococcus (GBS) is a major cause of neonatal sepsis, particularly because vulnerable newborns have underdeveloped intestinal barriers that allow GBS to invade.
- The study investigates the effects of butyrate, a fatty acid produced from dietary fiber fermentation, on GBS-induced damage to intestinal barriers and shows that butyrate reduces cell death and enhances barrier function.
- Maternal butyrate treatment in mice also leads to lower GBS levels in offspring, highlighting its potential as a preventive strategy against neonatal sepsis amid growing concerns of antibiotic resistance.
Injection-induced basement seismicity beneath the Raton Basin: constraints from refined fault architectures and basin structure.
Philos Trans A Math Phys Eng Sci
August 2024
Intraplate earthquakes induced by anthropogenic fluid injection present unexpected seismic risk to previously quiescent or low seismicity-rate regions. Despite many studies of induced seismicity, there are relatively few with detailed openly accessible constraints on the interaction between seismic sources and subsurface structures. In this study of the Raton Basin, we refine source observations from a dense nodal array and constrain basin structure using teleseismic receiver functions.
View Article and Find Full Text PDFProton magnetic resonance spectroscopy (H-MRS) is increasingly used for clinical brain tumour diagnosis, but suffers from limited spectral quality. This retrospective and comparative study aims at improving paediatric brain tumour classification by performing noise suppression on clinical H-MRS. Eighty-three/forty-two children with either an ependymoma (ages 4.
View Article and Find Full Text PDFH-magnetic resonance spectroscopy (MRS) has the potential to improve the noninvasive diagnostic accuracy for paediatric brain tumours. However, studies analysing large, comprehensive, multicentre datasets are lacking, hindering translation to widespread clinical practice. Single-voxel MRS (point-resolved single-voxel spectroscopy sequence, 1.
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