Publications by authors named "L Witthauer"

Background: Nocturnal hypoglycemia poses significant risks to individuals with insulin-treated diabetes, impacting health and quality of life. Although continuous glucose monitoring (CGM) systems reduce these risks, their poor accuracy at low glucose levels, high cost, and availability limit their use. This study examined physiological biomarkers associated with nocturnal hypoglycemia and evaluated the use of machine learning (ML) to detect hypoglycemia during nighttime sleep using data from consumer-grade smartwatches.

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Metrics derived from continuous glucose monitoring (CGM) systems are often discordant between systems. A major cause is that CGM systems are not standardized; they use various algorithms and calibration methods, leading to discordant CGM readings across systems. This discordance can be addressed by standardizing CGM performance assessments: If manufacturers aim their CGM systems at the same target, then CGM readings will align across systems.

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Article Synopsis
  • The study investigates how breath volatile organic compounds (VOCs) relate to glycaemic states in people with type 1 diabetes (T1D), aiming to identify VOCs that can serve as non-invasive biomarkers for hypoglycaemia.
  • Ten T1D individuals were placed in a controlled clinical setting to induce hypoglycaemia, while breath samples were collected and analyzed using advanced gas chromatography.
  • Results showed a strong correlation between specific VOCs, like isoprene and acetone, and blood glucose levels, with machine learning models achieving up to 93% accuracy in classifying glycaemic states, highlighting the potential for breath analysis in diabetes management.
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We report the measurement of the helicity asymmetry E for the pπ^{0} and nπ^{+} final states using, for the first time, an elliptically polarized photon beam in combination with a longitudinally polarized target at the Crystal Ball experiment at MAMI. The results agree very well with data that were taken with a circularly polarized photon beam, showing that it is possible to simultaneously measure polarization observables that require linearly (e.g.

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Aims: To examine the effects of a home-based exergame training over 6 weeks on cardio-metabolic and cognitive health, as well as training adherence, in physically inactive individuals.

Materials And Methods: Twenty participants were equipped with an exergame system specifically designed for use at home. Each participant performed at least three weekly exercise sessions at ≥80% of their individual maximum heart rate, over 6 weeks.

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