EF-hand calcium sensor, EfhP, controls transcriptional regulation of iron uptake by calcium in .

The human pathogen () poses a major risk for a range of severe infections, particularly lung infections in patients suffering from cystic fibrosis (CF). As previously reported, the virulent behavior of this pathogen is enhanced by elevated levels of Ca that are commonly present in CF nasal and lung fluids. In addition, a Ca-binding EF-hand protein, EfhP (PA4107), was partially characterized and shown to be critical for the Ca-regulated virulence in .

EF-Hand Calcium Sensor, EfhP, Controls Transcriptional Regulation of Iron Uptake by Calcium in .

Unlabelled: The human pathogen poses a major risk for a range of severe infections, particularly lung infections in patients suffering from cystic fibrosis (CF). As previously reported, the virulent behavior of this pathogen is enhanced by elevated levels of Ca that are commonly present in CF nasal and lung fluids. In addition, a Ca -binding EF-hand protein, EfhP (PA4107), was partially characterized and shown to be critical for the Ca -regulated virulence in .

Fungal Planet description sheets: 1112-1181.

Novel species of fungi described in this study include those from various countries as follows: , on soil, on leaves of on leaves of on leaves of sp., on soil, (incl. gen.

Correction: Widespread mortality of trembling aspen (Populus tremuloides) throughout interior Alaskan boreal forests resulting from a novel canker disease.

[This corrects the article DOI: 10.1371/journal.pone.

Widespread mortality of trembling aspen (Populus tremuloides) throughout interior Alaskan boreal forests resulting from a novel canker disease.

Over the past several decades, growth declines and mortality of trembling aspen throughout western Canada and the United States have been linked to drought, often interacting with outbreaks of insects and fungal pathogens, resulting in a "sudden aspen decline" throughout much of aspen's range. In 2015, we noticed an aggressive fungal canker causing widespread mortality of aspen throughout interior Alaska and initiated a study to quantify potential drivers for the incidence, virulence, and distribution of the disease. Stand-level infection rates among 88 study sites distributed across 6 Alaska ecoregions ranged from <1 to 69%, with the proportion of trees with canker that were dead averaging 70% across all sites.