Publications by authors named "L Wilkins-Haug"

Background: Genetic screening has advanced from prenatal cell-free DNA (cfDNA) screening for aneuploidies (cfDNA-ANP) to single-gene disorders (cfDNA-SGD). Clinical validation studies have been promising in pregnancies with anomalies but are limited in the general population.

Methods: Chart review and laboratory data identified pregnancies with cfDNA-SGD screening for 25 autosomal dominant conditions at our academic center.

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Article Synopsis
  • - The study examined the relationship between placental anomalies and fetal congenital heart disease (FCHD) to understand how these factors could impact infant health outcomes postnatally.
  • - Researchers analyzed placental samples from a total of 215 pregnancies with FCHD and 122 without, discovering significantly higher rates of maternal vascular malperfusion and cord anomalies in the FCHD group.
  • - Results indicated that while placental vascular malperfusion is common in FCHD, its prevalence does not vary based on the type of congenital heart disease, suggesting the need for further research on the interaction between placental health and fetal heart conditions.
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Background: FAV is offered to fetuses with severe aortic valve stenosis and evolving hypoplastic left heart syndrome. An inferential analysis of TS and SAE in a large series has not been reported.

Objectives: The purpose of this study was to determine factors associated with fetal aortic valvuloplasty (FAV) technical success (TS) and serious adverse events (SAEs).

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Background: Hypertensive disorders of pregnancy (HDP) are the most common cause of postpartum readmission. Prior research led to clinical guidelines for postpartum management; however, the patient experience is often missing from this work. The objective of this study is to understand the perspective of patients readmitted for postpartum hypertension.

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