Fine-needle aspiration biopsy and other biopsies in suspected intraocular malignant disease: a review.

Ocular oncologists require a strong indication for intraocular biopsy before the procedure can be performed because it carries a risk for serious eye complications and the dissemination of malignant cells. The purpose of this review is to evaluate the extent to which this restricted practice is supported by evidence from previous reports and to outline our main indications and contraindications. The different intraocular biopsy techniques in the anterior and posterior segment are discussed with a focus on our preferred method, fine-needle aspiration biopsy (FNAB).

Placental site trophoblastic tumor (PSTT) in mother and child: first report of PSTT in infancy.

Background: To the authors' knowledge, placental site trophoblastic tumors occurring simultaneously in mother and infant have not previously been reported.

Procedure: The clinicopathologic features of metastatic placental site trophoblastic tumor in a mother and her 4-month-old son are described.

Results: The disease in the infant was aggressive, and he died in multiorgan failure within 5 weeks of hospital admission.

Fine-needle aspiration biopsy diagnosis of a uveal metastasis from a follicular thyroid carcinoma.

Purpose: To report a rare tumour of the eye, and to illustrate the importance of performing a fine-needle aspiration biopsy.

Case Report: An 80-year-old woman suffering from general malaise, dyspnea and abdominal pain was found to have multiple lung metastases, a large tumour in the upper part of the mediastinum, and a large orange-brown tumour (19 x 15 x 11 mm) situated nasally in the left eye. Fine-needle aspiration biopsy of the uveal tumour and of the goitre was performed.

Fine needle aspiration biopsy in selecting treatment for inconclusive intraocular disease.

Purpose: To evaluate the fine needle aspiration biopsy (FNAB) as a diagnostic tool in cases where it was impossible to make a definitive diagnosis with noninvasive techniques.

Method: 80 consecutive patients with inconclusive diagnoses were examined by FNAB prior to decision of treatment. Biopsies were performed through a transscleral route in 50 eyes, an anterior chamber route in 16 eyes and a transvitreal approach in 14 eyes.

Extracranial metastasis of glioblastoma multiforme diagnosed by fine-needle aspiration: a report of two cases and a review of the literature.

Extracranial metastasis of cerebral glioblastoma is rarely seen. Craniotomy and diversionary shunt are widely accepted causes of dissemination. Prognosis is poor but new therapeutic modalities may improve the survival and lessen the patient's symptoms.