Publications by authors named "L Waddell"

Article Synopsis
  • - Blastomycosis is caused by fungi that can change from mold to yeast, primarily spread through inhalation of spores, often found in warm, wet soils, especially near forests and waterways.
  • - It is mostly found in Canada, particularly in Ontario and Manitoba, with Northwestern Ontario seeing high case rates; however, diagnosis can be delayed because symptoms resemble those of pneumonia or tuberculosis.
  • - Climate change might increase cases of blastomycosis due to shifts in temperature and rainfall, emphasizing the need for more research to predict its effects and improve prevention strategies.
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Background: Understanding the facilitators, barriers and hesitancy to accepting COVID-19 booster doses is important for encouraging recommended vaccination. This evidence brief summarizes literature on the intention to accept or reject COVID-19 vaccine booster doses and the factors associated with intention/uptake among individuals in Canada.

Methods: A database of COVID-19 literature established at the Public Health Agency of Canada was searched for articles referencing vaccination and knowledge, attitudes and behaviours towards COVID-19 boosters.

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Background: The COVID-19 pandemic underlined the need for pandemic planning but also brought into focus the use of mathematical modelling to support public health decisions. The types of models needed (compartment, agent-based, importation) are described. Best practices regarding biological realism (including the need for multidisciplinary expert advisors to modellers), model complexity, consideration of uncertainty and communications to decision-makers and the public are outlined.

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Background: Preprints are scientific articles that have not undergone the peer-review process. They allow the latest evidence to be rapidly shared, however it is unclear whether they can be confidently used for decision-making during a public health emergency. This study aimed to compare the data and quality of preprints released during the first four months of the 2022 mpox outbreak to their published versions.

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Article Synopsis
  • The study investigates how often MRI scans reveal unexpected but clinically significant findings in patients with knee osteoarthritis (KOA) suspected of having meniscal tears.
  • Out of 760 subjects who underwent MRIs, 61 (8.03%) were found to have notable findings such as subchondral insufficiency fractures, avascular necrosis, and tumors.
  • The results suggest that clinicians should consider a broader range of potential conditions underlying knee symptoms, as these incidental findings may require different management approaches and further imaging.
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