Maternal exposure to nicotine causes oxidative stress and inflammatory changes in the ovaries of adult rats' offspring.

Nicotine is one of the most toxic substances found in cigarettes, but also found in chewing tobacco gum, patches and vaping products (electronic cigarettes). In addition to being a highly addictive chemical, it is capable of reducing fertility in men and women. In the ovaries, it can induce morphological changes and impair the formation of follicles, being a possible cause of changes in the reproductive cycle and anticipation of menopause in women whose mothers smoked during pregnancy.

Lanternfish as bioindicator of microplastics in the deep sea: A spatiotemporal analysis using museum specimens.

We investigated MP ingestion in lanternfishes (Myctophidae), one of the most abundant vertebrates in the world, using archived specimens from museum collections from 1999 to 2017. Microplastics were detected in 55 % of the 1167 specimens analysed (0.95 ± 1.

The vacuolar phosphatases PAP26 and HIIA2.1 hydrolyze 5'-, 3'-, and 2'-nucleotides derived from RNA degradation.

The vacuole is an important site for RNA degradation. Autophagy delivers RNA to the vacuole, where the vacuolar T2 RNase Ribonuclease 2 (RNS2) plays a major role in RNA catabolism. The presumed products of RNS2 activity are 3'-nucleoside monophosphates (3'-NMPs).

Critical review on emerging photocatalytic membranes for pollutant removal: From preparation to application.

Due to synergistically enhanced separation and degradation performances, photocatalytic membranes offer an environmentally friendly and energy-sustainable method for water purification. However, a comprehensive review on preparation and application of photocatalytic membranes is still lacking. Systematically comparing different photocatalytic membrane fabrication methods and revealing the underlying mechanisms of their respective applications are of particular interest.

Precuneus activity during retrieval is positively associated with amyloid burden in cognitively normal older carriers.

The precuneus is a site of early amyloid-beta (Aβ) accumulation. Previous cross-sectional studies reported increased precuneus fMRI activity in older adults with mild cognitive deficits or elevated Aβ. However, longitudinal studies in early Alzheimer's disease (AD) are lacking and the relationship to the Apolipoprotein-E () genotype is unclear.