Publications by authors named "L W Deal"
Article Synopsis
- A study aimed to evaluate how consistent and accurate trained raters are when using two versions of the Vitiligo Area Scoring Index (T-VASI and F-VASI) to assess the severity of vitiligo in participants.
- Results showed that inter-rater reliability improved for facial assessments, while overall reliability for full-body assessments was consistently good, indicating the method is effective.
- Limitations included a small sample size and the lack of in-person evaluations, but the findings suggest the Vitiligo Area Scoring Index is a reliable tool for assessing vitiligo severity when used by trained individuals.
The Parkinson's Disease Activities of Daily Living, Interference, and Dependence Instrument© (PD-AID) is a patient-reported outcome (PRO) instrument, recently developed to assess the clinical benefit of Parkinson's Disease (PD) treatment. The PD-AID consists of morning and evening assessments, administered daily. To benefit from the full set of the repeated observations over time, analytic approaches that account for both within- and between-individual variability are required.
View Article and Find Full Text PDFIntroduction: This study explored patients' and dermatologists' priority outcomes for treatment to address, clinical outcome assessments (COA) for use in vitiligo clinical trials, and perceptions of within-patient meaningful change in facial and total body vitiligo.
Methods: Semistructured, individual, qualitative interviews were conducted with patients living with non-segmental vitiligo in the USA and with expert dermatologists in vitiligo. Concept elicitation discussions included open-ended questions to identify patient priority outcomes.
Parkinson's disease is a neurodegenerative disease that can be associated with motor fluctuations that result in substantial negative impact to an individual's activities of daily living. Understanding the patient's perspective about the impact of Parkinson's disease therapies is an important part of drug development and shared treatment decision-making. The objective of this research was to examine the structure, scoring, internal consistency, test-retest reliability, and concurrent and known groups validity of the Parkinson's Disease Activities of Daily Living, Interference and Dependence (PD-AID) instrument, a new, patient-reported outcomes instrument, developed to assess the clinical benefit of Parkinson's disease treatment from the patient's perspective.
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