FAT AND MUSCLE COMPONENTS OF BODY WEIGHT AND THEIR RELATIONSHIP WITH THE CONCENTRATION OF SERUM ADIPOKINES IN PATIENTS WITH NONALCOHOLIC FATTY LIVER DISEASE.

Objective: The aim: Identify differences in indexes of body fat and muscle masses, as well as blood adipokines in patients with nonalcoholic fatty liver disease, from gender-appropriate healthy men and women.

Patients And Methods: Materials and methods: 135 patients with non-alcoholic fatty liver disease with normal, overweight and obesity and 20 almost healthy individuals for the control group were examined. Verification of the diagnosis was performed in accordance with the recommendations of the unified clinical protocol.

[NON-CARDIAL EFFECTS OF SGLT2 INHIBITORS (REVIEW)].

The article reveals the efficacy and safety aspects of a new class of antidiabetic drugs - SGLT2 inhibitors. The results of clinical and experimental studies of the principle of renal glucose reabsorption inhibition usage in the treatment of type 2 diabetes are presented in the article. Drugs of this class offer a new, non-insulin-dependent mechanism of action, lack of negative effect on body weight, favorable pharmacokinetic properties and good tolerance.