Publications by authors named "L Vilella"
Article Synopsis
- The study aimed to evaluate the use of ultra-longterm EEG monitoring via a subcutaneous implantable device in adults with focal epilepsy to understand its clinical applications.* -
- Researchers analyzed medical records of 24 patients, identifying 11 main reasons for using long-term EEG recordings, such as detecting low-frequency seizures and distinguishing between epileptic and non-epileptic events.* -
- Findings suggest that while ultra-longterm monitoring can provide valuable diagnostic insights, there are limitations regarding its sensitivity and the ability to effectively monitor ongoing seizures.*
Article Synopsis
- The study aimed to investigate the occurrence of cardiac arrhythmias during generalized convulsive seizures (GCSs) and their potential link to sudden unexpected death in epilepsy (SUDEP).
- Researchers monitored adult epilepsy patients using video-EEG and various cardiological assessments to identify different types of arrhythmias occurring during seizures.
- The findings could provide insights into the relationship between seizure severity markers and cardiac arrhythmias, contributing to understanding the risk factors associated with SUDEP.
Objective: Stereo-electroencephalography (SEEG) is the preferred method for intracranial localization of the seizure-onset zone (SOZ) in drug-resistant focal epilepsy. Occasionally SEEG evaluation fails to confirm the pre-implantation hypothesis. This leads to a decision tree regarding whether the addition of SEEG electrodes (two-step SEEG - 2sSEEG) or placement of subdural electrodes (SDEs) after SEEG (SEEG2SDE) would help.
View Article and Find Full Text PDFObjective: Severe respiratory dysfunction induced by generalized convulsive seizures (GCS) is now thought to be a common mechanism for sudden unexpected death in epilepsy (SUDEP). In a mouse model of seizure-induced death, increased interictal respiratory variability was reported in mice that later died of respiratory arrest after GCS. We studied respiratory variability in epilepsy patients as a predictive tool for severity of postictal hypoxemia, a potential biomarker for SUDEP risk.
View Article and Find Full Text PDFCurrently, there is some ambiguity over the role of postictal generalized electro-encephalographic suppression (PGES) as a biomarker in sudden unexpected death in epilepsy (SUDEP). Visual analysis of PGES, known to be subjective, may account for this. In this study, we set out to perform an analysis of PGES presence and duration using a validated signal processing tool, specifically to examine the association between PGES and seizure features previously reported to be associated with visually analyzed PGES.
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