Publications by authors named "L Vaugier"
Article Synopsis
- * Recent advancements in immunotherapy have improved treatment options for non-small-cell lung cancer (NSCLC), but SCLC still poses significant challenges due to its aggressive nature and high chances of recurrence or metastasis.
- * The article discusses the emerging role of stereotactic radiotherapy in managing small-cell lung cancer, similar to its established use in treating early-stage NSCLC and metastatic diseases.
Introduction: Up to 30% patients newly diagnosed with advanced non-small cell lung cancer (NSCLC) present with brain metastases. In the absence of oncogenic addiction, first-line immunotherapy, alone or in combination with chemotherapy, is the current standard of care. This review aims to synthesize the available data regarding the efficacy of immunotherapy in these patients, and to discuss the possibility of its being coordinated with local treatments such as radiotherapy.
View Article and Find Full Text PDFCryotherapy is an ablative therapy that can be used to treat localized prostate cancer. In case of recurrence, treatment options are not well-defined, and their outcomes are unknown. We therefore collected all patients treated with radiotherapy after cryotherapy for prostate cancer recurrence in Nantes (France) between 2012 and 2019.
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- Androgen deprivation therapy (ADT) combined with elective nodal radiotherapy (ENRT) shows promising long-term outcomes for men with limited prostate cancer recurrence, specifically targeting pelvic lymph nodes.
- In a trial involving 67 patients, after a median follow-up of over 6 years, a significant proportion experienced prolonged tumor control with manageable levels of toxicities.
- After 5 years, about one-third of patients remained free from biochemical relapse, highlighting ENRT's effectiveness in maintaining remission and delaying disease progression.
There are currently no accurate rules for manually delineating the subregions of the heart (cavities, vessels, aortic/mitral valves, Planning organ at Risk Volumes for coronary arteries) with the perspective of deep-learning based modeling. Our objective was to present a practical pictorial view for radiation oncologists, based on the RTOG atlas and anatomical complementary considerations for the cases where the RTOG guidelines are missing.
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