Publications by authors named "L Vang"
Article Synopsis
- Mitochondria are important parts of cells that help with energy and can influence cancer growth and how well treatments work.
- Researchers studied a type of aggressive breast cancer called triple negative breast cancer (TNBC) to understand how the structure of mitochondria changes when treated with chemotherapy.
- They found that chemotherapy can change the shape and size of mitochondria in tumors, differing in treated tumors compared to those that weren't treated, suggesting that understanding these changes could help improve cancer treatment strategies.
Evaluation of phytotoxic potential in Asteraceae plant extracts for biological control of and .
Plant Environ Interact
October 2024
This study evaluates the phytotoxic potential of methanolic extracts from six Asteraceae species: , , , , , . The extracts were tested at concentrations of 0.03, 0.
View Article and Find Full Text PDFThe physical characteristics of brown adipose tissue (BAT) are defined by the presence of multilocular lipid droplets (LDs) within the brown adipocytes and a high abundance of iron-containing mitochondria, which give it its characteristic color. Normal mitochondrial function is, in part, regulated by organelle-to-organelle contacts. For example, the contact sites that mediate mitochondria-LD interactions are thought to have various physiological roles, such as the synthesis and metabolism of lipids.
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- The liver experiences aging-related decline in mitochondrial function, leading to increased risk of liver diseases, as structural changes in mitochondria and metabolism are observed.
- The study uses advanced imaging techniques to analyze how mitochondrial structure and size alter with age in mice, while also revealing metabolic shifts in older samples.
- Key findings include the loss of the MICOS complex and reduction of the SAM50 protein, both of which are linked to increased susceptibility to liver diseases, highlighting the role of diet and aging in these processes.
The kidney filters nutrient waste and bodily fluids from the bloodstream, in addition to secondary functions of metabolism and hormone secretion, requiring an astonishing amount of energy to maintain its functions. In kidney cells, mitochondria produce adenosine triphosphate (ATP) and help maintain kidney function. Due to aging, the efficiency of kidney functions begins to decrease.
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