Background: In South Africa, one in five adolescents experience pregnancy and face heightened rates of interpersonal violence and mental health challenges. Yet, few interventions are tailored to them.
Methods: 28 pregnant adolescents reporting past year intimate partner violence and/or non-partner rape were purposively recruited in antenatal clinics in Johannesburg to attend a 6-session arts-based intervention, delivered by 4 graduate art therapy students alongside clinical supervision.
Introduction: The COVID-19 pandemic was a public health emergency (PHE) of unprecedented magnitude and impact. It provided the possibility to investigate the Dutch citizens' understanding and perception of the actors involved in the Dutch pandemic response as a PHE unfolded.
Methods: Three focus groups (FGs) were held with 16 Dutch citizens in June 2020.
The effect of dietary energy and lysine levels on laying persistency and body composition in brown and white hens was studied. Dietary treatments with 2 Metabolizable Energy levels (ME lay; constant or reduction over time) and 2 apparent fecal digestible Lys levels (AFD Lys; constant or reduction over time), were fed to Lohmann white or brown hens, from 17 to 75 wk of age, in a 2 × 2 × 2 factorial design. Data were subjected to mixed model analyses.
View Article and Find Full Text PDFAngew Chem Int Ed Engl
November 2024
Protein homeostasis in bacteria is regulated by proteases such as the tetradecameric caseinolytic protease P (ClpP). Although substrates of ClpP have been successfully deciphered in genetically engineered cells, methods which directly trap processed proteins within native cells remain elusive. Here, we introduce an in situ trapping strategy which utilizes trifunctional probes that bind to the active site serine of ClpP and capture adjacent substrates with an attached photocrosslinking moiety.
View Article and Find Full Text PDFUnderstanding the effect of nutrition on pullet growth curves and body composition may help to design new feeding strategies that influence body composition and (long-term) laying performance. Therefore, this study examined the effect of nutrient density (low, medium or high metabolizable energy and essential amino acids), fed in the rearing phase until 17 wk of age, on Hy-Line white W80 pullet growth, body composition development and egg production performance until wk 35. Data were subjected to mixed model analyses.
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