[Tissue changes in the oral cavity of children with primary immunodeficiency states].

The examination of 89 children aged 3-14 with diverse forms of primary immunodeficiency (ID) demonstrated that the most intensive progress of caries, mucosal inflammation and the worst oral hygiene occurred in cellular ID, especially in children with chronic generalized skin and mucosal candidiasis. Antibody defects of immunity enhanced caries in dental hard tissues. Phagocytic defects were also associated with dental caries, disorders of oral mucosa, unsatisfactory oral hygiene.

[Metabolic effect of gutimine on the myocardial tissue in blood loss].

A rate of hemorrhage accounted for 31 mg/kg in 80 adult dogs premedicated with promedol and atropine. After circular-hemic hypoxia caused by the hemorrhage, single intravenous administration of gutimine (35-40 mg/kg) transformed the carbohydrate metabolism in heart muscle: activated glycolysis and accelerated the rate of its products oxidation, maintained the free amino acids concentration at the level similar to that of intact animals, reduced the rate of creatine phosphate synthesis.