[Characterization of a Rif-R population of Bacillus anthracis].

Formation of spontaneous RifR mutants was detected in the populations of various strains of Bacillus anthracis (STI-1, Sterne and CH-7) at a rate of 10(-8) per 1 CFU. The levels of the rifampicin resistance in the mutants were different, the MIC ranged from 16 to 512 micrograms/ml. The clones of the RifR population of the virulent strain CH-7 were heterogeneous in the morphological properties of the colonies and cells, the capacity for the synthesis of the toxin and capsule, the sporulation and virulence.

[Interaction of bacillus anthracis with benzylpenicillin in vivo and in vitro].

Interaction of the cells of Bacillus anthracis strain CH-7 with benzylpenicillin was studied. The cells of strain CH-7 were shown to contain the penicillinase gene in the repressed state. Spontaneous derepression of the gene at a rate of 10(-8) resulting in the synthesis of penicillinase was observed.

[Induced methanol dehydrogenase in the yeast Hansenula polymorphia DL-1].

The yeast Hansenula polymorpha DL-I showed NAD-specific dehydrogenase activity involved in the methanol primary oxidation. This enzyme was found to be induced during periodic and continuous H. polymorpha cultivation, using methanol as the sole source of carbon and energy.