[PCR-detection of cytomegalovirus infection in oncologic and non-oncologic patients with organ and tissue transplantation].

Cytomegalovirus (CMV) infection often causes death after organ transplantation. Therefore, adequate prevention, diagnosis and treatment of this complication are of critical importance. The experience of establishing routine PCR-detection of CMV is presented.

[The effect of hemosorption on the immunological status of patients with acute destructive pancreatitis].

Patients with acute destructive pancreatitis were found to have pronounced changes in the immune system manifesting themselves by reduced general amount of lymphocytes mainly at the expense of T-lymphocytes with helper and suppressor activity and in less degree--at the expense of B-lymphocytes, increase of poorly differentiated O-cells, reduction of immunoglobulin C. Hemosorption on the sorbent SKN promotes more rapid recovery of indices of the immune system in the group of patients with the area of injured pancreas less than 50% and is practically ineffective for its total injury.

[Immunomodulating therapy in perforated peritonitis].

The immunological responsiveness was studied in 160 patients with generalized peritonitis. In the postoperative period, 51 patients underwent immunomodulating therapy. The highest effect was produced by transfusion of 300-400 ml leukoconcentrate.

[Various immunologic indices in primary chronic adrenal insufficiency].

Patients with primary chronic adrenal insufficiency (PCAI) in decompensation demonstrated a decrease in the total level of blood immunoglobulins, in particular IgG, with the normal level of B-lymphocytes. A decrease in IgG and an increase in IgA content was noted in the eucorticoid state; relative and absolute lymphocytosis determined by an increase in T- and B-lymphocytes was also noted. In overdosage of cortisone acetate the total number of immunoglobulins was normal, but IgA was raised and IgG lowered.