[Lactae dehydrogenase activity and its isoenzymatic spectrum in the myocardium in rheumatic heart defects].

The activity of lactate dehydrogenase (LDH) and its isoenzymatic spectrum were studied in biopsy specimen of the myocardium of 35 patients with mitral valvular disease who underwent operation. Starch gel electrophoresis was used. Four fractions of LDH isoenzymes were detected: LDH1, LDH2, LDH3, and LDH4.

[Effect of fat loading on the development of silicosis].

Rats were administered with quartz dust intratracheally or subjected to chronic inhalation of the dust. Peroral overloading of rats with fat was shown to increase an accumulation of all lipid fractions in lungs and intensified silicotic fibrinogenesis. Similar alterations in lipid metabolism of lungs were observed in control animals maintained without the dust treatment at the same fatty diet; but these patterns were less distinct and were not accompanied by an increased collagene formation.