[The dependence of the efficacy of cyclosporin A use in a kidney allograft on the degree of donor and recipient tissue compatibility based on HLA-DR antigens].

Upon the analyses of outcomes of 69 primary allogenic kidney transplantations it was noted that cyclosporin A immunosuppressive potential grew in transplantation of the kidney more compatible by HLA-DR antigens. It follows that it would be valid to perform tissue selection in the above use of the drug cyclosporin A.

[Serologic polymorphism of the HLA Class 2 antigens in the Russian population].

Two hundred and thirty Russian Moscovities (108 healthy individuals and 122 cadaver kidney donors) were typed for antigens HLA-DR1-DRw10, HLA-DRw52-DRw53, and HLA-DQw1 and DQw3. HLA-DR1, 2, 3, 4, 5 and 7 were investigated in all individuals, the other having been only studied in portions of the material. The HLA class 2 antigens' polymorphism in Russian population has been shown to have features common to all Caucasians.

[Polymorphism of the HLA genetic system in Khanty population].

Serological polymorphism of HLA 1 class genes and antigens (A, B, C) was studied in native West-Siberian population of Khants. Genes HLA-A2, A23, A24, B7, B35, B49, Cw4 and Cw7 appeared to be most frequent in this population. HLA-A23/B49 was the most wide-spread haplotype with strong linkage disequilibrium.