[Neural network modeling of triiodothyronine concentrations by the levels of lymphocytic NADP-dependent dehydrogenases in patients with thyroid hypo- and hyperfunction].

Whether a computer model which calculates serum triiodothyronine concentrations (T3) can be constructed by the levels of metabolic enzymes in the immunocompetent cells by means of a neural network predictor of real numbers. For this, the concentration of serum T3 and the activity lymphocytic NADP-dependent dehydrogenases were determined by radioimmune assay and bioluminescence technique, respectively. It was found that the neural network prediction might be only in each examined group alone.

[Activity of NADP-dependent dehydrogenase of thymocytes and blood lymphocytes after irradiation of rabbits in vivo with long-wave laser radiation].

To study the mechanisms of immunocompetent cells' response to long-wave laser radiation in male Chinchilla rabbits after in vivo emission (lambda = 632.8 nm; emissive power, 19 mW) for 15 min, lymphocytes and thymocytes were identified in the projection areas of the thymus and femur and the levels of NADP-dependent dehydrogenases were measured. The changes found in the levels of thymocyte NADP-dependent dehydrogenases while exposing the rabbits to radiation in the area of the femur, as well as the area-related differences in the modulating effects of laser radiation on the activity of the lymphocytic enzymes under study indicate the mediated cellular metabolic regulation which is likely to be chiefly affected by the autonomic nervous system in the first postradiation minutes.