[Possibilities of using the method of crystallography of tears in pathologies of the lacrimal apparatus].

A total of 178 patients with pathologies in the lacrimal apparatus (including 81 patients with dacryocystitis, 51 patients with imperforation of the lacrimal canals' opening and 46 patients with dacryostenosis) were investigated. Crystallographic examination (CGE) of the lacrimal fluid was made for both eyes before and after surgery. 32 virtually healthy persons made up the control group.

[The prevention and treatment of recurrences after dacryorhinostomies].

A total of 1206 dacryorhinostomies carried out from January, 1991 to December, 1997 at Institute of Ocular Diseases of the Russian Academy of Medical Sciences are analyzed. The main causes of relapses were underevaluation of the data of examinations and improper choice of operative access and method of surgery, errors in the technique of operation, and wrong postoperative treatment. For improving the efficacy of surgery, the authors developed a comprehensive method for preventing and treating relapses.

[Intubation granulomas of the lacrimal ducts in patients with silicone implants].

The results of 315 endonasal operations on the lacrimal duct with long intubation are analyzed. The most incident complication of long intubation of the lacrimal duct is formation of intubation granulomas, which are most often localized in the inferior lacrimal canaliculus; their etiology is sometimes allergic--they form as a response of adjacent tissues to the material of the intubation tube, and the findings of our recent histological study prove it. The diagnosis of intubation granulomas is easy in the majority of cases.

[Effect of ACTH4-10 on the course of inflammatory and regeneration processes in the rabbit cornea].

The effect of synthetic peptide ACTH4-10 on the course of healing of an experimental wound of the rabbit cornea was studied. Daily subconjunctival injections of the drug in a dose of 10(-8) M for 25 days boosted the migration of leukocytes and macrophages and increased the interstitial and keratocyte proteolysis during the first 10 days of the experiment. Subsequent follow-up showed manifest proliferation of fibroblasts and formation of fibrosis.

[Effects of protein S-100 beta on the course of corneal healing in rabbits].

Effects of S-100 beta protein on wound healing in rabbit eye cornea were studied. A subconjunctival injection of the protein was found to lead to earlier epithelialization, decrease of the index of migrating inflammation cells, and prevention of fibrous subepithelial growth. Hence, administration of S-100 beta protein resulted in a more effective and rapid healing of the cornea.