[Experimental pneumonia caused by an association of H. influenzae and the influenza virus].

Experiments in 400 non-inbred white mice indicated that the association of influenza virus A2 Hong Kong with H. influenzae enhanced the pathogenic action of the causative agents and led to the unfavorable clinical outcome only in those cases when these agents penetrated the body simultaneously, or when viral infection preceded bacterial infection. In those cases when influenza infection appeared in the presence of bacterial infection, the pathological process developed as a monoviral disease.

[Morphogenesis of complicated and uncomplicated influenza].

Changes in the lungs in the prodromal period immediately after inoculation of animals with influenza virus were studied at length by electron microscopy. An early involvement in the process of pulmonary alveolar cells was demonstrated. Particular attention is drawn to viral and viral-bacterial associations determining the severity of the course of influenza and its lethal outcomes.

[Experimental influenza caused by an incomplete form of the agent].

Incomplete form of the influenza virus obtained in accordance with Nayak's method was administered intranasally to mice CBA and C57BL. From the lung tissue of the infected mice the causative agent could be isolated for 45 days, and from the other internal organs--the first hours after the infection only. In morphological investigation of the lungs of animals infected with an incomplete form of the influenza virus a prevalence of the proliferative component against the background of inflammatory changes was noted.

[Significance of the heterogeneity of an influenza virus population in the cytopathology of influenzal infection].

Separation of the allantoic cultures of influenza A/Hong Kong/68 and A/England/72 viruses on DEAE-Sephadex-A-50 with 1/15 M phosphate buffer solution containing 0.1, 0.5, and 1.