[Characteristics of the activation of type E. Cl. botulinum toxins].

Molecular changes occurring in type E. Cl. botulinum single-chain toxin as the result of treatment with trypsin under different conditions were studied.

[Isolation and properties of highly purified C1. botulinum toxin type E].

A new method of isolation of highly purified Cl. botulinum toxin of E type from the cultural fluid of strain 188 centrifugates was developed. The method allows to isolate the toxin both in a precursor and in activated forms with a yield of 10--15%.