PD-L1 Expression in Nonbacterial Chronic Cystitis and Bladder Cancer.

Introduction And Hypothesis: The objective was to assess PD-L1 expression in nonbacterial chronic cystitis (NCC) and bladder cancer (BC).

Methods: The present study included 20 NCC and 20 BC patients. The degree of inflammation of the bladder wall was assessed on slides stained with H&E.

[A prognostic value of level of antiviral antibodies in the development of recurrence of bladder cancer].

Introduction: Serological diagnosis of virus-associated tumors attracts the attention of many specialists. The changes in the level of antiviral antibodies in tumors of different localizations are proved. In some cases, the authors suggest using these data either for screening of tumors or for controlling the cure.

[High oncogenic risk human papillomavirus and urinary bladder cancer].

Aim: To determine the role of human papillomavirus (HPV) of high oncogenic risk in the development of urinary bladder cancer.

Materials And Methods: 100 patients (72 men and 28 women) aged 38 to 90 years (mean age 65+/-10 years) diagnosed with bladder cancer were examined and underwent treatment. Clinical assessment was complemented by enzyme-linked immunosorbent assays for the presence of antiviral antibodies to herpes simplex virus (HSV) type 1 and type 2, cytomegalovirus (CMV), Epstein-Barr virus (EBV), urethra scraping for detecting high oncogenic risk HPV.

[A retrospective analysis of morphological tests in patients with interstitial cystitis].

Cystoscopy, hydrobougieurage and biopsy of the urinary bladder were made in 80 female patients with interstitial cystitis (IC) aged 23-68 years. Endoscopic changes were estimated by an original scale. The analysis of the endoscopic findings revealed a correlation between duration of the process, cystoscopic picture and histopathological evidence.

Change in the ploidy of prostatic epitheliocyte nuclei during carcinogenesis.

Comparative computer-assisted microspectrophotometric analysis of histological preparations showed that the mean nuclear ploidy increased 1.3 times in glandular hyperplasia and 2-fold in adenocarcinoma of 3 progressive degrees of dysdifferentiation. Proliferative activity of cells also increased from stage to stage.