[Genotoxic effect of acrylates].

Study of mutagenic activity of butylacrylate and methyl methacrylate on bone marrow cells of rat was carried out. Mutagenic activity of both of them was noted, but the butylacrylate was more active.

[Mutagenic and cytotoxic effects of acrylates].

Increasing amount of fructose-1-phosphate aldolase activity in rat blood serum and induction of chromosomal aberrations in rat bone marrow cells were observed after injection of acrylamide. The cytotoxic activity of acrylamide in rat depended on the dose. Methylmethacrylate and butyl methacrylate demonstrated no such activity.