Grassland restoration is an important conservation intervention supporting declining insect pollinators in threatened calcareous grassland landscapes. While the success of restoration is often quantified using simple measures of diversity or similarity to target communities, these measures do not capture all fundamental aspects of community reconstruction. Here, we develop species-habitat networks that aim to define habitat-level foraging dependencies of pollinators across restored grassland landscapes and compare their value to these more conventional measures of community restoration.
View Article and Find Full Text PDFGut Microbes
October 2024
Most of the short-chain fatty acids (SCFAs) are produced by , , Lachnospiraceae, , , , and . Butyrate (CHO) supplies 70% of energy to intestinal epithelial cells (IECs), supports tight-junction protein formation, induces the production of inflammatory cytokines, and inhibits histone deacetylase (HDAC). Butyrate is also associated with the recovery of brain trauma, improvement of dementia, the alleviation of autoimmune encephalitis, and several intestinal disorders.
View Article and Find Full Text PDFCardiovascular disease (CVD) may be inherited, as recently shown with the identification of single nucleotide polymorphisms (SNPs or "snips") on a 250 kb DNA fragment that encodes 92 proteins associated with CVD. CVD is also triggered by microbial dysbiosis, microbial metabolites, metabolic disorders, and inflammatory intestinal epithelial cells (IECs). The epithelial cellular adhesion molecule (Ep-CAM) and trefoil factor 3 (TFF3) peptide keeps the gut wall intact and healthy.
View Article and Find Full Text PDFIn this study, an in silico screening approach was employed to mine potential bacteriocin clusters in genome-sequenced isolates of Lacticaseibacillus zeae UD 2202 and Lacticaseibacillus casei UD 1001. Two putative undescribed bacteriocin gene clusters (Cas1 and Cas2) closely related to genes encoding class IIa bacteriocins were identified. No bacteriocin activity was recorded when cell-free supernatants of strains UD 2202 and UD 1001 were tested against Listeria monocytogenes.
View Article and Find Full Text PDFViridisin A1 and A2 were previously heterologously expressed, purified, and characterized as ribosomally produced and post-translationally modified lanthipeptides. Such lanthipeptide operons are surprisingly common in Gram-negative bacteria, although their expression seems to be predominantly cryptic under laboratory conditions. However, the bioactivity and biological role of most lanthipeptide operons originating from marine-associated , such as XOM25T, have not been described.
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