[Participation of the gastrointestinal tract in regulating the processes of insulin liberation by the pancreas].

Three elevations of the insulin concentration in the blood of the v. pancreaticoduodenalis and v. portae were found in dogs fed with food containing mainly proteins, fat or carbohydrates.

[Insulin secretion in dogs with experimental pancreatitis to the intrapancreatic administration of glucose].

Early immunoreactive insulin and glucose alterations were studied in the pancreatoduodenal vein of dogs with experimental hepatitis after rapid glucose injection into the pancreatic artery. The blood was collected from the pancreatoduodenal vein every 10 s. In the early period of insulin release the stimulant effect of glucose on insulin secretion was less pronounced in animals with experimental hepatitis as compared with control.

[Dynamics of insulin secretion in dogs with alloxan diabetes].

It was shown that hypoinsulinemia in the superior pancratico-duodenal vein and inhibition of the first phase of insulin secretion by the pancreas characteristic of alloxan diabetes of different severity was absent in the femoral vein. The data obtained in the insulin and glucose concentration study in the superior pancreatico-duodenal vein stressed the leading role of the pancreatic factor in the pathogenesis of alloxan diabetes in dogs. Analysis of these parameters in the peripheral femoral vein failed to reflect this statement adequately.