Publications by authors named "L V Boeck"
In people with HIV-1 (PWH), (MTB) infection poses a significant threat. While active tuberculosis (TB) accelerates immunodeficiency, the interaction between MTB and HIV-1 during asymptomatic phases remains unclear. Analysis of peripheral blood mononuclear cells (PBMC) transcriptomic profiles in PWH, with and without controlled viral loads, revealed distinct clustering in MTB-infected individuals.
View Article and Find Full Text PDFMicrobial metabolism disrupts cytokine activity to impact host immune response.
Proc Natl Acad Sci U S A
November 2024
Host-pathogen interactions are shaped by the metabolic status of both the host and pathogen. The host must regulate metabolism to fuel the immune response, while the pathogen must extract metabolic resources from the host to enable its own survival. In this study, we focus on the metabolic interactions of with .
View Article and Find Full Text PDFArticle Synopsis
- * A supercritical fluid chromatography technique was developed to simultaneously identify and quantify seven alkaloids in less than six minutes, showing high precision and accuracy per ICH guidelines.
- * The study also applied this method to isolate five specific alkaloids from a crude extract using centrifugal partition chromatography, achieving good yields and confirming their purity with further analysis.