Publications by authors named "L V"
People with chronic pain mitigate their suffering by the action of opioids. Adverse reactions aside, opioids are not exempt from potential complications like addiction and abuse, which have posed a global public health problem lately. Finding new therapeutic strategies to improve analgesia and to reduce opioid side effects has become a priority.
View Article and Find Full Text PDFE-cadherin is a cell adhesion molecule crucial for maintaining cellular integrity and survival. E-cadherin is the focus of this study, which aims to evaluate its immunohistochemical staining patterns in endometrial carcinoma (EC). Material and methods In this retrospective study, 25 formalin-fixed, paraffin-embedded tissue blocks of EC were retrieved from the Department of Pathology at Saveetha Medical College.
View Article and Find Full Text PDFAim: This study aims to compare and assess the compression strength, microhardness, and surface texture of two sets of materials: mineral trioxide aggregate (MTA) Plus and bacterial cellulose nanocrystal (BCNC)-reinforced MTA Plus.
Materials And Methods: According to the ASTM E384 standard, the cylindrical molds made of plexiglass with an internal diameter of 6 mm and a height of 4 mm were fabricated using computer numerical control laser cutting. A total of 20 samples (n=10) in each group were considered in this experimental study: Group I (control group) MTA Plus (Prevest DenPro Limited, India) and Group II (experimental group) BCNC (Vedayukt India Private Limited, India)-reinforced MTA Plus.
Article Synopsis
- Phyllodes tumors (PTs) are rare breast tumors that vary in severity from benign growths (like fibroadenomas) to malignant forms, complicating diagnosis and treatment.
- Malignant PTs have a high chance of recurrence and poor outcomes, underscoring the need for careful histopathological evaluation and genetic research to improve diagnosis and potential therapies.
- The article discusses a case of malignant PT in a 74-year-old woman, highlighting the tumor's ability to mimic other types of breast cancer and the important role of immunohistochemistry in accurately diagnosing these tumors.
The hobnail variant of papillary thyroid carcinoma (HVPTC) represents a distinctive and relatively rare histological subtype of thyroid malignancies. This variant is characterized by its unique cellular morphology with a hobnail appearance, that is, cells with apically positioned nuclei. There are other characteristics like micropapillary pattern and loss of cohesiveness of cells, which are indicative of HVPTC.
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