Publications by authors named "L Turchetto"
Article Synopsis
- Ganz's studies allowed for better treatment of joint deformities in Perthes' disease via femoral head reduction osteotomy (FHRO) and periacetabular osteotomy (PAO), improving joint structure and function.
- A study conducted from 2015 to 2021 involved 13 FHRO procedures on 11 patients, using CT and MRI to plan corrections and assess outcomes through various clinical and radiological metrics.
- Results indicated significant improvements in joint shape and patient-reported outcomes, with no major complications, demonstrating the effectiveness of the combined surgical approach.
The development of an extracellular vesicles (EV)-based therapeutic product requires the implementation of reproducible and scalable, purification protocols for clinical-grade EV. Commonly used isolation methods including ultracentrifugation, density gradient centrifugation, size exclusion chromatography, and polymer-based precipitation, faced limitations such as yield efficiency, EV purity, and sample volume. We developed a GMP-compatible method for the scalable production, concentration, and isolation of EV through a strategy involving, tangential flow filtration (TFF).
View Article and Find Full Text PDF(1) Introduction: Intraoperative preservation solutions for saphenous vein grafts may influence the endothelial structure and increase the risk of graft failure after coronary surgery. The aim of the study was to compare the efficacy of three solutions in maintaining the endothelial cell integrity of venous segments. (2) Methods: We tested the efficacy of physiological saline solution (PSS), heparinized autologous blood (HAB) and DuraGraft in preserving the endothelium of vein segments by evaluating the degree of endothelial cell apoptosis.
View Article and Find Full Text PDFBackground: The modified Dunn procedure (MDP) has risen enthusiasm in treating slipped capital femoral epiphyses (SCFE) due to the anatomic reduction and high patients' satisfaction rates at long-term follow-up. Main aim of this study is to compare clinical and radiographic outcomes of 2 cohorts with moderate to severe stable SCFE treated by MDP and fixation.
Methods: Medical records were analysed to collect demographic data, comorbidities and time from slip to surgery.